Insights and opportunities for deep brain stimulation as a brain circuit intervention
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
the dynamic circuit architecture of brain disorders. This Review illustrates our current …
Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …
Pathological pallidal beta activity in Parkinson's disease is sustained during sleep and associated with sleep disturbance
Parkinson's disease (PD) is associated with excessive beta activity in the basal ganglia.
Brain sensing implants aim to leverage this biomarker for demand-dependent adaptive …
Brain sensing implants aim to leverage this biomarker for demand-dependent adaptive …
[HTML][HTML] Spectral and spatial distribution of subthalamic beta peak activity in Parkinson's disease patients
Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …
Beta: bursts of cognition
Beta oscillations are linked to the control of goal-directed processing of sensory information
and the timing of motor output. Recent evidence demonstrates they are not sustained but …
and the timing of motor output. Recent evidence demonstrates they are not sustained but …
Pallidal Beta Activity Is Linked to Stimulation‐Induced Slowness in Dystonia
R Lofredi, U Scheller, A Mindermann… - Movement …, 2023 - Wiley Online Library
Background Pallidal deep brain stimulation (DBS) effectively alleviates symptoms in
dystonia patients, but may induce movement slowness as a side‐effect. In Parkinson's …
dystonia patients, but may induce movement slowness as a side‐effect. In Parkinson's …
Cortical beta oscillations map to shared brain networks modulated by dopamine
Brain rhythms can facilitate neural communication for the maintenance of brain function.
Beta rhythms (13–35 Hz) have been proposed to serve multiple domains of human ability …
Beta rhythms (13–35 Hz) have been proposed to serve multiple domains of human ability …
Modulation of subthalamic beta oscillations by movement, dopamine, and deep brain stimulation in Parkinson's disease
Abstract Subthalamic beta band activity (13–35 Hz) is known as a real-time correlate of
motor symptom severity in Parkinson's disease (PD) and is currently explored as a feedback …
motor symptom severity in Parkinson's disease (PD) and is currently explored as a feedback …
Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making
CW Hoy, C de Hemptinne, SS Wang… - Proceedings of the …, 2024 - pnas.org
Choosing whether to exert effort to obtain rewards is fundamental to human motivated
behavior. However, the neural dynamics underlying the evaluation of reward and effort in …
behavior. However, the neural dynamics underlying the evaluation of reward and effort in …
Machine learning explains response variability of deep brain stimulation on Parkinson's disease quality of life
Improving health-related quality of life (QoL) is crucial for managing Parkinson's disease.
However, QoL outcomes after deep brain stimulation (DBS) of the subthalamic nucleus …
However, QoL outcomes after deep brain stimulation (DBS) of the subthalamic nucleus …