Reward functioning in PTSD: a systematic review exploring the mechanisms underlying anhedonia

L Nawijn, M van Zuiden, JL Frijling, SBJ Koch… - Neuroscience & …, 2015 - Elsevier
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder. An important
diagnostic feature of PTSD is anhedonia, which may result from deficits in reward …

Rethinking post-traumatic stress disorder–A predictive processing perspective

T Kube, M Berg, B Kleim, P Herzog - Neuroscience & Biobehavioral …, 2020 - Elsevier
Predictive processing has become a popular framework in neuroscience and computational
psychiatry, where it has provided a new understanding of various mental disorders. Here …

Hypothesis: the psychedelic ayahuasca heals traumatic memories via a sigma 1 receptor-mediated epigenetic-mnemonic process

A Inserra - Frontiers in pharmacology, 2018 - frontiersin.org
Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and
epigenetic regulation. N, N-Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) …

A predictive coding account of value-based learning in PTSD: Implications for precision treatments

A Putica, KL Felmingham, MI Garrido… - Neuroscience & …, 2022 - Elsevier
While there are a number of recommended first-line interventions for posttraumatic stress
disorder (PTSD), treatment efficacy has been less than ideal. Generally, PTSD treatment …

Defining the r factor for post-trauma resilience and its neural predictors

SJH van Rooij, JL Santos, CA Hinojosa, TD Ely… - Nature Mental …, 2024 - nature.com
Although resilience is a dynamic process of recovery after trauma, in most studies it is
conceptualized as the absence of specific psychopathology following trauma. Here, using …

The role of the hippocampus in predicting future posttraumatic stress disorder symptoms in recently traumatized civilians

SJH van Rooij, JS Stevens, TD Ely, R Hinrichs… - Biological …, 2018 - Elsevier
Background Understanding the neurobiological mechanisms that predict posttraumatic
stress disorder (PTSD) in recent trauma survivors is important for early interventions …

Psychological and brain connectivity changes following trauma-focused CBT and EMDR treatment in single-episode PTSD patients

E Santarnecchi, L Bossini, G Vatti, A Fagiolini… - Frontiers in …, 2019 - frontiersin.org
Among the different therapeutic alternatives for post-traumatic stress disorder (PTSD),
Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) and Eye Movement …

Neural correlates of inhibition and contextual cue processing related to treatment response in PTSD

SJ Van Rooij, E Geuze, M Kennis… - …, 2015 - nature.com
Thirty to fifty percent of posttraumatic stress disorder (PTSD) patients do not respond to
treatment. Understanding the neural mechanisms underlying treatment response could …

Partial and total sleep deprivation interferes with neural correlates of consolidation of fear extinction memory

J Seo, EF Pace-Schott, MR Milad, H Song… - Biological Psychiatry …, 2021 - Elsevier
Background We assessed the impact of total and partial sleep loss on neural correlates of
fear conditioning, extinction learning, and extinction recall in healthy young adults. Methods …

Circuit dysregulation and circuit-based treatments in posttraumatic stress disorder

J Sheynin, I Liberzon - Neuroscience Letters, 2017 - Elsevier
Posttraumatic stress disorder (PTSD) is a psychiatric disorder that develops in some
individuals in the aftermath of exposure to traumatic events, such as actual or threatened …