Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

[HTML][HTML] Bias in artificial intelligence algorithms and recommendations for mitigation

LH Nazer, R Zatarah, S Waldrip, JXC Ke… - PLOS digital …, 2023 - journals.plos.org
The adoption of artificial intelligence (AI) algorithms is rapidly increasing in healthcare. Such
algorithms may be shaped by various factors such as social determinants of health that can …

Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the Writing Committee of the American Society for Apheresis: the …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

The pathophysiology of sepsis and precision-medicine-based immunotherapy

EJ Giamarellos-Bourboulis, AC Aschenbrenner… - Nature …, 2024 - nature.com
Sepsis remains a major cause of morbidity and mortality in both low-and high-income
countries. Antibiotic therapy and supportive care have significantly improved survival …

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

P Póvoa, L Coelho, F Dal-Pizzol, R Ferrer… - Intensive care …, 2023 - Springer
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

A Tabah, N Buetti, Q Staiquly, S Ruckly, M Akova… - Intensive care …, 2023 - Springer
Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated
with significant mortality. Granular data are required for optimizing management, and …

The immunology of sepsis

T van der Poll, M Shankar-Hari, WJ Wiersinga - Immunity, 2021 - cell.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. This recently implemented definition does not capture the …

Early restrictive or liberal fluid management for sepsis-induced hypotension

National Heart, Lung, and Blood Institute … - … England Journal of …, 2023 - Mass Medical Soc
Background Intravenous fluids and vasopressor agents are commonly used in early
resuscitation of patients with sepsis, but comparative data for prioritizing their delivery are …

Stress ulcer prophylaxis during invasive mechanical ventilation

D Cook, A Deane, F Lauzier, N Zytaruk… - … England Journal of …, 2024 - Mass Medical Soc
Background Whether proton-pump inhibitors are beneficial or harmful for stress ulcer
prophylaxis in critically ill patients undergoing invasive ventilation is unclear. Methods In this …

2023 update on sepsis and septic shock in adult patients: management in the emergency department

M Guarino, B Perna, AE Cesaro, M Maritati… - Journal of clinical …, 2023 - mdpi.com
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …