Steroid sulfation and desulfation are fundamental pathways vital for a functional vertebrate
endocrine system. After biosynthesis, hydrophobic steroids are sulfated to expedite …

Hormones regulate homeostasis by communicating through the bloodstream to the body's
organs, including the brain. As homeostatic regulators of brain function, some hormones …

The potent estrogen 17β-Estradiol (E 2) plays a critical role in mediating hippocampal
function, yet the precise mechanisms through which E 2 enhances hippocampal memory …

Estrogen is one of the most important female sex hormones, and is indispensable for
reproduction. However, its role is much wider. Among others, due to its neuroprotective …

A wide range of health benefits have been ascribed to soya intake including a lowered risk
of osteoporosis, heart disease, breast cancer, and menopausal symptoms. Because it is a …

Multiple lines of evidence indicate that androgens, such as testosterone, modulate the
mesocorticolimbic system and executive function. This review integrates neuroanatomical …

Patients surviving traumatic brain injury (TBI) face numerous neurological and
neuropsychological problems significantly affecting their quality of life. Extensive studies …

Context Vitamin D status is conventionally defined by measurement of unconjugated
circulating 25-hydroxyvitamin D (25OHD), but it remains uncertain whether this isolated …

Across invertebrates and vertebrates, steroids are potent signaling molecules that affect
nearly every cell in the organism, including cells of the nervous system. Historically …

Steroid hormones can modulate motivated behaviors through the mesocorticolimbic system.
Gonadectomy (GDX) is a common method to determine how steroids influence the …