Systems pharmacology approaches in herbal medicine research: a brief review

M Lee, H Shin, M Park, A Kim, S Cha, H Lee - BMB reports, 2022 - pmc.ncbi.nlm.nih.gov
Herbal medicine, a multi-component treatment, has been extensively practiced for treating
various symptoms and diseases. However, its molecular mechanism of action on the human …

Phytochemical Insights into Ficus sur Extracts and Their Biological Activity

E Sieniawska, Ł Świątek, KI Sinan, G Zengin… - Molecules, 2022 - mdpi.com
This study focused on the biological evaluation and chemical characterisation of Ficus sur
Forssk.(F. sur)(Family: Moraceae). The methanolic and aqueous extracts' phytochemical …

Combination of UHPLC-MS/MS with context-specific network and cheminformatic approaches for identifying bioactivities and active components of propolis

YR Cho, KA Jo, S Park, J Choi, G Kim, TY Kim… - Food Research …, 2023 - Elsevier
Discovering new bioactivities and identifying active compounds of food materials are major
fields of study in food science. However, the process commonly requires extensive …

A deep learning-based approach for identifying the medicinal uses of plant-derived natural compounds

S Yoo, HC Yang, S Lee, J Shin, S Min, E Lee… - Frontiers in …, 2020 - frontiersin.org
Medicinal plants and their extracts have been used as important sources for drug discovery.
In particular, plant-derived natural compounds, including phytochemicals, antioxidants …

Predicting herb-disease associations using network-based measures in human protein interactome

S Wang, HC Lee, S Lee - BMC Complementary Medicine and Therapies, 2024 - Springer
Background Natural herbs are frequently used to treat diseases or to relieve symptoms in
many countries. Moreover, as their safety has been proven for a long time, they are …

UHPLC-QTOF-MS phytochemical profiling and in vitro biological properties of Rhamnus petiolaris (Rhamnaceae)

G Rocchetti, MB Miras-Moreno, G Zengin… - Industrial Crops and …, 2019 - Elsevier
The genus Rhamnus has a great attention as source of bioactive compounds. So, this work
aimed to investigate phytochemical profile and biological activity of water and methanolic …

[HTML][HTML] Systems biology approaches reveal potential phenotype-modifier genes in neurofibromatosis Type 1

T Woycinck Kowalski, L Brussa Reis, T Finger Andreis… - Cancers, 2020 - mdpi.com
Neurofibromatosis type (NF1) is a syndrome characterized by varied symptoms, ranging
from mild to more aggressive phenotypes. The variation is not explained only by genetic and …

Enhancing intestinal health with germinated oats: Bioinformatics and compound profiling insights into a novel approach for managing inflammatory bowel disease

HJ Lee, KJ Kim, S Park, K Choi, J Pyee, S Yoo, JY Kim - Food Bioscience, 2024 - Elsevier
Oats are widely recognized for their numerous health benefits, particularly regarding their
anti-inflammatory properties. However, research exploring their specific effects on intestinal …

SYmptom-based STratification of DiabEtes mellitus by renal function decline (system): a retrospective cohort study and modeling assessment

KW Chan, TY Chow, KY Yu, Y Xu, NL Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Previous UK Biobank studies showed that symptoms and physical
measurements had excellent prediction on long-term clinical outcomes in general …

Identification of molecular mechanism of the anti-lung cancer effect of ** Ning Fang using network pharmacology and its experimental verification

C Wu, Q Yu, W Shou, K Zhang, Y Li, W Guo, Q Bao - All Life, 2022 - Taylor & Francis
** Ning Fang (JNF), a classic Chinese medicine formula, is widely used to treat lung
cancer. However, its molecular mechanism remains unclear. Thus, we aimed to explore the …