Although the clinical demand for bioengineered blood vessels continues to rise, current
options for vascular conduits remain limited. The synergistic combination of emerging …

The Blood Brain Barrier (BBB) is a specialized vascular structure tightly regulating central
nervous system (CNS) homeostasis. Endothelial cells are the central component of the BBB …

Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …

A role for fibroblasts in physiological and pathological angiogenesis is now well recognized;
however, the precise mechanisms underlying their action have not been determined. Using …

The extracellular matrix (ECM) is critical for all aspects of vascular biology. In concert with
supporting cells, endothelial cells (ECs) assemble a laminin-rich basement membrane …

Angiogenesis, or the formation of new blood vessels from the preexisting vasculature, is a
key component in numerous physiologic and pathologic responses and has broad impact in …

We show that endothelial cell (EC)–generated vascular guidance tunnels (ie, matrix spaces
created during tube formation) serve as conduits for the recruitment and motility of pericytes …

Angiogenesis is defined as a new blood vessel sprouting from pre-existing vessels. This
highly regulated process take place through two non-exclusive events, the so-called …

How do animal cells assemble into tissues and organs? A diverse array of tissue structures
and shapes can be formed by organizing groups of cells into different polarized …

Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult,
angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement …