Exposure to environmental hazards has been associated with diseases in humans. The
identification of single nucleotide polymorphisms (SNPs) in human populations exposed to …

Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as
lung allergens and irritants. Exposure to these substances can lead to inflammatory …

Chronic obstructive pulmonary disease (COPD) is a severe lung disease characterized by
long‐term breathing problems. A series of studies have indicated that the glutathione S …

Increasing evidence suggest that occupational exposure to open-cast coal mining residues
like dust particles, heavy metals and Polycyclic Aromatic Hydrocarbons (PAHs) may cause a …

Background Chronic myeloid leukemia (CML) is associated to the BCR-ABL1 oncogene and
can successfully be treated with tyrosine kinase inhibitors (TKIs). However, it remains still …

The variations between different individuals in the xenobiotic metabolizing enzymes' activity
were shown to modify susceptibility to childhood acute lymphoblastic leukemia (ALL) …

ABSTRACT Introduction Adverse drug reactions (ADRs) pose a significant challenge in
clinical practice, impacting patient safety and treatment outcomes. Genetic variations in drug …

Cyclophosphamide is one of the most potent and reliable anti-cancer and
immunosuppressive drugs. In our study, 33 individuals with different autoimmune diseases …

Background There are several meta-analyses on the genetic relationship between the
rs1695 polymorphism within the GSTP1 (glutathione S-transferase pi 1) gene and the risk of …

Attention deficit and hyperactivity disorder (ADHD) is highly heritable disorder and common
in school-age children characterized by inattention, hyperactivity and impulsivity. Although …