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Physical models of collective cell migration
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
Mechanobiology of collective cell behaviours
The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …
including morphogenesis, cancer progression and tissue remodelling, largely depends on …
Ultra-strong bio-glue from genetically engineered polypeptides
The development of biomedical glues is an important, yet challenging task as seemingly
mutually exclusive properties need to be combined in one material, ie strong adhesion and …
mutually exclusive properties need to be combined in one material, ie strong adhesion and …
Physics of microswimmers—single particle motion and collective behavior: a review
Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search
for food, orientation toward light, spreading of off-spring, and the formation of colonies are …
for food, orientation toward light, spreading of off-spring, and the formation of colonies are …
Single and collective cell migration: the mechanics of adhesions
Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …
or apoptosis in the long term. However, to be able to move and migrate through a complex …
Unjamming and cell shape in the asthmatic airway epithelium
From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of
close-packed collective systems—both inert and living—have the potential to jam. The …
close-packed collective systems—both inert and living—have the potential to jam. The …
Physics of active jamming during collective cellular motion in a monolayer
Although collective cell motion plays an important role, for example during wound healing,
embryogenesis, or cancer progression, the fundamental rules governing this motion are still …
embryogenesis, or cancer progression, the fundamental rules governing this motion are still …
Active cell migration is critical for steady-state epithelial turnover in the gut
Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal
epithelial turnover is marked by continuous cell migration, which is assumed to be driven by …
epithelial turnover is marked by continuous cell migration, which is assumed to be driven by …
Spontaneous shear flow in confined cellular nematics
In embryonic development or tumour evolution, cells often migrate collectively within
confining tracks defined by their microenvironment,. In some of these situations, the …
confining tracks defined by their microenvironment,. In some of these situations, the …
All roads lead to directional cell migration
Directional cell migration normally relies on a variety of external signals, such as chemical,
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …