[HTML][HTML] Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic
involving so far more than 22 million infections and 776,157 deaths. Effective vaccines are …
involving so far more than 22 million infections and 776,157 deaths. Effective vaccines are …
Epigenetic patterns in a complete human genome
The completion of a telomere-to-telomere human reference genome, T2T-CHM13, has
resolved complex regions of the genome, including repetitive and homologous regions …
resolved complex regions of the genome, including repetitive and homologous regions …
Intratumor heterogeneity in early lung adenocarcinoma
Lung cancer is one of the deadliest diseases in the world and is the leading cause of cancer-
related deaths. Among the histological types, adenocarcinoma is the most common, and it is …
related deaths. Among the histological types, adenocarcinoma is the most common, and it is …
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system
Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing
protein family (NLRs) are intracellular pattern recognition receptors that mediate innate …
protein family (NLRs) are intracellular pattern recognition receptors that mediate innate …
Platelet MHC class I mediates CD8+ T-cell suppression during sepsis
L Guo, S Shen, JW Rowley, ND Tolley… - Blood, The Journal …, 2021 - ashpublications.org
Circulating platelets interact with leukocytes to modulate host immune and thrombotic
responses. In sepsis, platelet-leukocyte interactions are increased and have been …
responses. In sepsis, platelet-leukocyte interactions are increased and have been …
Immune response to SARS-CoV-2 infection in obesity and T2D: literature review
J Pérez-Galarza, C Prócel, C Cañadas, D Aguirre… - Vaccines, 2021 - mdpi.com
In December 2019, a novel coronavirus known as SARS-CoV-2 was first detected in Wuhan,
China, causing outbreaks of the coronavirus disease COVID-19 that has now spread …
China, causing outbreaks of the coronavirus disease COVID-19 that has now spread …
Making cold malignant pleural effusions hot: driving novel immunotherapies
P Murthy, CN Ekeke, KL Russell, SC Butler… - …, 2019 - Taylor & Francis
Malignant pleural effusions, arising from either primary mesotheliomas or secondary
malignancies, heralds advanced disease and poor prognosis. Current treatments, including …
malignancies, heralds advanced disease and poor prognosis. Current treatments, including …
Human leukocyte antigen (HLA) system: genetics and association with bacterial and viral infections
The human leukocyte antigen (HLA) system is one of the most crucial host factors
influencing disease progression in bacterial and viral infections. This review provides the …
influencing disease progression in bacterial and viral infections. This review provides the …
The Association between TNF-alpha, IL-1 alpha and IL-10 with Alzheimer's Disease
Background: Sporadic Alzheimer's Disease (AD) is assumed to be associated with different
biological/genetic vulnerability, as well as with neuroinflammation, mediated by cytokines …
biological/genetic vulnerability, as well as with neuroinflammation, mediated by cytokines …
Computing skin cutaneous melanoma outcome from the HLA-alleles and clinical characteristics
Human leukocyte antigen (HLA) are essential components of the immune system that
stimulate immune cells to provide protection and defense against cancer. Thousands of HLA …
stimulate immune cells to provide protection and defense against cancer. Thousands of HLA …