Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the
neuronal compartment, but includes strong interactions with immunological mechanisms in …

The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …

Over the last decade knowledge of the role of astrocytes in central nervous system (CNS)
neuroinflammatory diseases has changed dramatically. Rather than playing a merely …

Alzheimer's disease (AD) is a neurodegenerative disorder with no clear causative event
making the disease difficult to diagnose and treat. The pathological hallmarks of AD include …

Emerging evidences about gut-microbial modulation have been accumulated in the
treatment of nonalcoholic fatty liver disease (NAFLD). We evaluated the effect of …

Traumatic brain injury (TBI) provokes inflammatory responses, including a dramatic rise in
brain macrophages in the area of injury. The pathway (s) responsible for macrophage …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
formation of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques …

The central nervous system (CNS) is the most important section of the nervous system as it
regulates the function of various organs. Injury to the CNS causes impairment of …

Chemokines are important modulators of neuroinflammation and neurodegeneration. In the
brains of Alzheimer's disease (AD) patients and in AD animal models, the chemokine …