Albuminuria is the hallmark of both primary and secondary proteinuric glomerulopathies,
including focal segmental glomerulosclerosis (FSGS), obesity-related nephropathy, and …

Ever since loss of survival motor neuron (SMN) protein was identified as the direct cause of
the childhood inherited neurodegenerative disorder spinal muscular atrophy, significant …

Background It is confirmed that adipose-derived stem cells (ADSCs) transplantation
effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome …

Abstract Background Bisphenol A (BPA) is a widespread endocrine-disrupting chemical with
estrogen like effects, which could interfere with the human reproductive system by disrupting …

Diabetic nephropathy (DN) together with glomerular hyperfiltration has been implicated in
the development of diabetic microangiopathy in the initial stage of diabetic diseases …

Focal segmental glomerulosclerosis (FSGS) describes both a common lesion in progressive
kidney disease, and a disease characterized by marked proteinuria and podocyte injury …

The glomerulus is a highly specialized capillary tuft, which under pressure filters large
amounts of water and small solutes into the urinary space, while retaining albumin and large …

Targeted protein degradation (TPD) through the autophagy pathway displays broad
substrate scope and is gaining increasing interest in biology and medicine. However …

In 1923, Dr. Warburg had observed that tumors acidified the Ringer solution when 13 mM
glucose was added, which was identified as being due to lactate. When glucose is the only …

Membranous nephropathy (MN, also known as membranous glomerulopathy) is one of the
many glomerular diseases causing nephrotic syndrome. The literature indicates that …