The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Importance Low levels of vitamin D are associated with elevated blood pressure (BP) and
future cardiovascular events. Whether vitamin D supplementation reduces BP and which …

Context Vitamin D is associated with decreased cardiovascular-related morbidity and
mortality, possibly by modifying cardiac structure and function, yet firm evidence for either …

Background Despite treatment with renin–angiotensin–aldosterone system (RAAS)
inhibitors, patients with diabetes have increased risk of progressive renal failure that …

The discovery of the vitamin D endocrine system and a receptor for the hormonal form, 1α,
25-dihydroxyvitamin D3, has brought a new understanding of the relationship between …

Vitamin D deficiency is common and is primarily caused by a lack of ultraviolet-B (UVB)
radiation from reduced sun exposure, and the consequent limiting of vitamin D production in …

Background: To our knowledge, there is no study that has examined the effects of vitamin D
supplementation on metabolic status in gestational diabetes mellitus (GDM). Objective: This …

Background: Vitamin D may decrease depression symptoms through its beneficial effects on
neurotransmitters, metabolic profiles, biomarkers of inflammation, and oxidative stress …

Results FGF23 correlated directly with IL-6 (r= 0.4), CRP (r= 0.2), TNF-α (r= 0.4), and
fibrinogen (r= 0.3; P< 0.001 for each). In univariate and multivariable-adjusted linear …

Recent studies implicate Wnt/β-catenin signaling in podocyte dysfunction. Because vitamin
D analogs can inhibit β-catenin in other tissues, we tested whether the vitamin D analog …