Manipulating microbial cell morphology for the sustainable production of biopolymers

VC Kalia, SKS Patel, KK Karthikeyan, M Jeya, IW Kim… - Polymers, 2024 - mdpi.com
The total rate of plastic production is anticipated to surpass 1.1 billion tons per year by 2050.
Plastic waste is non-biodegradable and accumulates in natural ecosystems. In 2020, the …

Microbial engineering for easy downstream processing

Y Wang, C Ling, Y Chen, X Jiang, GQ Chen - Biotechnology Advances, 2019 - Elsevier
Downstream is a very expensive process for microbial fermentation. It usually involves
complicated equipment and processes to obtain desired chemicals or materials from intra …

Peptidoglycan: structure, synthesis, and regulation

S Garde, PK Chodisetti, M Reddy - EcoSal Plus, 2021 - journals.asm.org
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …

Spotlight on FtsZ-based cell division in Archaea

S Ithurbide, S Gribaldo, SV Albers, N Pende - Trends in Microbiology, 2022 - cell.com
Compared with the extensive knowledge on cell division in model eukaryotes and bacteria,
little is known about how archaea divide. Interestingly, both endosomal sorting complex …

The role of GpsB in Staphylococcus aureus cell morphogenesis

SF Costa, BM Saraiva, H Veiga, LB Marques… - Mbio, 2024 - journals.asm.org
For decades, cells of the Gram-positive bacterial pathogen Staphylococcus aureus were
thought to lack a dedicated elongation machinery. However, S. aureus cells were recently …

Stress-induced adaptive morphogenesis in bacteria

E Ultee, K Ramijan, RT Dame, A Briegel… - Advances in microbial …, 2019 - Elsevier
Bacteria thrive in virtually all environments. Like all other living organisms, bacteria may
encounter various types of stresses, to which cells need to adapt. In this chapter, we …

A fly on the wall: how stress response systems can sense and respond to damage to peptidoglycan

A Delhaye, JF Collet, G Laloux - Frontiers in Cellular and Infection …, 2019 - frontiersin.org
The envelope of Gram-negative bacteria is critical for survival across a wide range of
environmental conditions. The inner membrane, the periplasm and the outer membrane …

Cell wall deficiency as a co** strategy for stress

D Claessen, J Errington - Trends in microbiology, 2019 - cell.com
The cell wall is a surface layer located outside the cell membrane of almost all bacteria; it
protects cells from environmental stresses and gives them their typical shape. The cell wall …

Crosslink cleaving enzymes: the smart autolysins that remodel the bacterial cell wall

V Rajguru, S Chatterjee, S Garde, M Reddy - Trends in Microbiology, 2024 - cell.com
Peptidoglycan (PG) is a protective mesh-like polymer in bacterial cell walls that enables their
survival in almost every ecological niche. PG is formed by crosslinking of several glycan …

Understanding beta-lactam-induced lysis at the single-cell level

F Wong, S Wilson, R Helbig, S Hegde… - Frontiers in …, 2021 - frontiersin.org
Mechanical rupture, or lysis, of the cytoplasmic membrane is a common cell death pathway
in bacteria occurring in response to β-lactam antibiotics. A better understanding of the …