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Indication and management of allogeneic haematopoietic stem-cell transplantation in myelofibrosis: updated recommendations by the EBMT/ELN International …
New options for medical therapy and risk scoring systems containing molecular data are
leading to increased complexity in the management of patients with myelofibrosis. To inform …
leading to increased complexity in the management of patients with myelofibrosis. To inform …
Novel developments in the prophylaxis and treatment of acute GVHD
Acute graft-versus-host disease (aGVHD) is a major life-threatening complication after
allogeneic hematopoietic cell transplant. Traditional standard prophylaxis for aGVHD has …
allogeneic hematopoietic cell transplant. Traditional standard prophylaxis for aGVHD has …
Vedolizumab for the prevention of intestinal acute GVHD after allogeneic hematopoietic stem cell transplantation: a randomized phase 3 trial
Acute graft-versus-host disease (aGVHD) of the lower gastrointestinal (GI) tract is a major
cause of morbidity and mortality in patients receiving allogeneic hematopoietic stem cell …
cause of morbidity and mortality in patients receiving allogeneic hematopoietic stem cell …
Post-transplant cyclophosphamide–based graft-versus-host disease prophylaxis attenuates disparity in outcomes between use of matched or mismatched unrelated …
BC Shaffer, M Gooptu, TE DeFor, M Maiers… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Access to allogeneic hematopoietic cell transplantation (HCT) remains limited
among persons of non-European ancestry if human leukocyte antigen (HLA) matching is …
among persons of non-European ancestry if human leukocyte antigen (HLA) matching is …
PTCy versus ATG as graft-versus-host disease prophylaxis in mismatched unrelated stem cell transplantation
O Penack, M Abouqateb, C Peczynski… - Blood Cancer …, 2024 - nature.com
There is an increased risk of GVHD and of non-relapse mortality (NRM) after allogeneic
stem cell transplantations (alloSCT) when mismatched unrelated donors (MMUD) are used …
stem cell transplantations (alloSCT) when mismatched unrelated donors (MMUD) are used …
ATG or post-transplant cyclophosphamide to prevent GVHD in matched unrelated stem cell transplantation?
O Penack, M Abouqateb, C Peczynski, W Boreland… - Leukemia, 2024 - nature.com
There is a high risk of GVHD and non-relapse mortality (NRM) after allogeneic stem cell
transplantations (alloSCT) from unrelated donors. Prophylaxis with rabbit anti-thymocyte …
transplantations (alloSCT) from unrelated donors. Prophylaxis with rabbit anti-thymocyte …
Younger unrelated donors may be preferable over HLA match in the PTCy era: a study from the ALWP of the EBMT
There is a paucity of information on how to select the most appropriate unrelated donor (UD)
in hematopoietic stem cell transplantation (HSCT) using posttransplant cyclophosphamide …
in hematopoietic stem cell transplantation (HSCT) using posttransplant cyclophosphamide …
Human leukocyte antigen mismatching and survival in contemporary hematopoietic cell transplantation for hematologic malignancies
PURPOSE Human leukocyte antigen (HLA) mismatching can reduce survival of patients
with blood cancer after hematopoietic cell transplantation (HCT). How recent advances in …
with blood cancer after hematopoietic cell transplantation (HCT). How recent advances in …
[HTML][HTML] Current approaches for the prevention and treatment of acute and chronic GVHD
A Olivieri, G Mancini - Cells, 2024 - mdpi.com
Whereas aGVHD has strong inflammatory components, cGVHD displays autoimmune and
fibrotic features; incidence and risk factors are similar but not identical; indeed, the aGVHD is …
fibrotic features; incidence and risk factors are similar but not identical; indeed, the aGVHD is …
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML
We conducted a phase 1 trial assessing safety and efficacy of prophylactic maintenance
therapy with venetoclax and azacitidine (Ven/Aza) for patients with high-risk myelodysplastic …
therapy with venetoclax and azacitidine (Ven/Aza) for patients with high-risk myelodysplastic …