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Sequestration of Proteins in Stress Granules Relies on the In-Cell but Not the In Vitro Folding Stability
Stress granules (SGs) are among the most studied membraneless organelles that form upon
heat stress (HS) to sequester unfolded, misfolded, or aggregated protein, supporting protein …
heat stress (HS) to sequester unfolded, misfolded, or aggregated protein, supporting protein …
Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease
S Blumenstock, EK Schulz‐Trieglaff, K Voelkl… - The EMBO …, 2021 - embopress.org
The cellular protein quality control machinery is important for preventing protein misfolding
and aggregation. Declining protein homeostasis (proteostasis) is believed to play a crucial …
and aggregation. Declining protein homeostasis (proteostasis) is believed to play a crucial …
Biosensors for studying neuronal proteostasis
I Dudanova - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Cellular health depends on the integrity and functionality of the proteome. Each cell is
equipped with a protein quality control machinery that maintains protein homeostasis …
equipped with a protein quality control machinery that maintains protein homeostasis …