Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

Construction of living artificial cells from genes and molecules can expand our
understanding of life system and establish a new aspect of bioengineering. However, growth …

Exogenous fatty acid (eFA) activation and utilization play key roles in bacterial physiology
and confer growth advantages by bypassing the need to make fatty acids for lipid synthesis …

Bacterial pathogens and viruses are the leading causes of global waterborne diseases.
Here, we discovered an interesting natural paradigm of water “self-purification” through virus …

A group of Gram-negative plant-associated diazotrophic bacteria belonging to the genus
Nitrospirillum was investigated, including both previously characterized and newly isolated …

Membranes contain lipids that are composed of fatty acids (FA) and a polar head.
Membrane homeostasis is crucial for optimal bacterial growth and interaction with the …

PlsX plays a central role in the coordination of fatty acid and phospholipid biosynthesis in
Gram-positive bacteria. PlsX is a peripheral membrane acyltransferase that catalyzes the …

A key aspect in membrane biogenesis is the coordination of fatty acid to phospholipid
synthesis rates. In most bacteria, PlsX is the first enzyme of the phosphatidic acid synthesis …

Phase separation is essential for membrane function, and alterations in phase coexistence
by membrane-interacting molecules, such as nicotine, can impair membrane stability. With …

Background Hepatocellular carcinoma (HCC) is a serious life-threatened tumor with high
morbidity and mortality. This study aimed to study the effects of combination TACE and anti …