The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements
YL Chiu, WC Greene - Annu. Rev. Immunol., 2008 - annualreviews.org
All retroviruses, including HIV-1, display species-specific patterns of infection. The impaired
growth of these retroviruses in foreign and sometimes even in their natural hosts often stems …
growth of these retroviruses in foreign and sometimes even in their natural hosts often stems …
Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system
TAP Driedonks, ENM Nolte-'t Hoen - Frontiers in immunology, 2019 - frontiersin.org
The exchange of extracellular vesicles (EV) between immune cells plays a role in various
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …
Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions
L Vojtech, S Woo, S Hughes, C Levy… - Nucleic acids …, 2014 - academic.oup.com
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but
which could also interfere with defense against infection. Each ejaculate contains trillions of …
which could also interfere with defense against infection. Each ejaculate contains trillions of …
Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion
Cardiosphere‐derived cells (CDC s) reduce myocardial infarct size via secreted
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …
Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain
Neuronal ELAV-like (nELAVL) RNA binding proteins have been linked to numerous
neurological disorders. We performed crosslinking-immunoprecipitation and RNAseq on …
neurological disorders. We performed crosslinking-immunoprecipitation and RNAseq on …
Map** the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition
JL Goodier, LE Cheung… - Nucleic acids research, 2013 - academic.oup.com
LINE1s occupy 17% of the human genome and are its only active autonomous mobile DNA.
L1s are also responsible for genomic insertion of processed pseudogenes and> 1 million …
L1s are also responsible for genomic insertion of processed pseudogenes and> 1 million …
High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition
YL Chiu, HE Witkowska, SC Hall… - Proceedings of the …, 2006 - National Acad Sciences
APOBEC3G (A3G) and related deoxycytidine deaminases are potent intrinsic antiretroviral
factors. A3G is expressed either as an enzymatically active low-molecular-mass (LMM) form …
factors. A3G is expressed either as an enzymatically active low-molecular-mass (LMM) form …
Ro60 and Y RNAs: structure, functions, and roles in autoimmunity
Ro60, also known as SS-A or TROVE2, is an evolutionarily conserved RNA-binding protein
that is found in most animal cells, approximately 5% of sequenced prokaryotic genomes and …
that is found in most animal cells, approximately 5% of sequenced prokaryotic genomes and …
Y-RNA subtype ratios in plasma extracellular vesicles are cell type-specific and are candidate biomarkers for inflammatory diseases
TAP Driedonks, S Mol, S de Bruin… - Journal of …, 2020 - Taylor & Francis
Major efforts are made to characterize the presence of microRNA (miRNA) and messenger
RNA in blood plasma to discover novel disease-associated biomarkers. MiRNAs in plasma …
RNA in blood plasma to discover novel disease-associated biomarkers. MiRNAs in plasma …
YRNAs and YRNA-derived fragments as new players in cancer research and their potential role in diagnostics
K Guglas, I Kołodziejczak, T Kolenda… - International Journal of …, 2020 - mdpi.com
YRNAs are a type of short, noncoding RNAs. A total of four different transcripts can be
distinguished, which are YRNA1, YRNA3, YRNA4 and YRNA5. All YRNAs are relatively …
distinguished, which are YRNA1, YRNA3, YRNA4 and YRNA5. All YRNAs are relatively …