The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements

YL Chiu, WC Greene - Annu. Rev. Immunol., 2008 - annualreviews.org
All retroviruses, including HIV-1, display species-specific patterns of infection. The impaired
growth of these retroviruses in foreign and sometimes even in their natural hosts often stems …

Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system

TAP Driedonks, ENM Nolte-'t Hoen - Frontiers in immunology, 2019 - frontiersin.org
The exchange of extracellular vesicles (EV) between immune cells plays a role in various
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

L Vojtech, S Woo, S Hughes, C Levy… - Nucleic acids …, 2014 - academic.oup.com
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but
which could also interfere with defense against infection. Each ejaculate contains trillions of …

Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

L Cambier, G de Couto, A Ibrahim… - EMBO Molecular …, 2017 - embopress.org
Cardiosphere‐derived cells (CDC s) reduce myocardial infarct size via secreted
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

C Scheckel, E Drapeau, MA Frias, CY Park, J Fak… - Elife, 2016 - elifesciences.org
Neuronal ELAV-like (nELAVL) RNA binding proteins have been linked to numerous
neurological disorders. We performed crosslinking-immunoprecipitation and RNAseq on …

Map** the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

JL Goodier, LE Cheung… - Nucleic acids research, 2013 - academic.oup.com
LINE1s occupy 17% of the human genome and are its only active autonomous mobile DNA.
L1s are also responsible for genomic insertion of processed pseudogenes and> 1 million …

High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

YL Chiu, HE Witkowska, SC Hall… - Proceedings of the …, 2006 - National Acad Sciences
APOBEC3G (A3G) and related deoxycytidine deaminases are potent intrinsic antiretroviral
factors. A3G is expressed either as an enzymatically active low-molecular-mass (LMM) form …

Ro60 and Y RNAs: structure, functions, and roles in autoimmunity

M Boccitto, SL Wolin - Critical reviews in biochemistry and …, 2019 - Taylor & Francis
Ro60, also known as SS-A or TROVE2, is an evolutionarily conserved RNA-binding protein
that is found in most animal cells, approximately 5% of sequenced prokaryotic genomes and …

Y-RNA subtype ratios in plasma extracellular vesicles are cell type-specific and are candidate biomarkers for inflammatory diseases

TAP Driedonks, S Mol, S de Bruin… - Journal of …, 2020 - Taylor & Francis
Major efforts are made to characterize the presence of microRNA (miRNA) and messenger
RNA in blood plasma to discover novel disease-associated biomarkers. MiRNAs in plasma …

YRNAs and YRNA-derived fragments as new players in cancer research and their potential role in diagnostics

K Guglas, I Kołodziejczak, T Kolenda… - International Journal of …, 2020 - mdpi.com
YRNAs are a type of short, noncoding RNAs. A total of four different transcripts can be
distinguished, which are YRNA1, YRNA3, YRNA4 and YRNA5. All YRNAs are relatively …