Sha** up synthetic cells

Y Mulla, A Aufderhorst-Roberts… - Physical biology, 2018 - iopscience.iop.org
How do the cells in our body reconfigure their shape to achieve complex tasks like migration
and mitosis, yet maintain their shape in response to forces exerted by, for instance, blood …

Multicompartment polymer vesicles with artificial organelles for signal‐triggered cascade reactions including cytoskeleton formation

A Belluati, S Thamboo, A Najer… - Advanced Functional …, 2020 - Wiley Online Library
Organelles, ie, internal subcompartments of cells, are fundamental to spatially separate
cellular processes, while controlled intercompartment communication is essential for signal …

Branched actin cortices reconstituted in vesicles sense membrane curvature

L Baldauf, F Frey, MA Perez, T Idema, GH Koenderink - Biophysical journal, 2023 - cell.com
The actin cortex is a complex cytoskeletal machinery that drives and responds to changes in
cell shape. It must generate or adapt to plasma membrane curvature to facilitate diverse …

Benefits and challenges of reconstituting the actin cortex

BE Waechtler, R Jayasankar, EP Morin… - …, 2024 - Wiley Online Library
The cell's ability to change shape is a central feature in many cellular processes, including
cytokinesis, motility, migration, and tissue formation. The cell constructs a network of …

Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis

F Farina, N Ramkumar, L Brown… - The EMBO …, 2019 - embopress.org
Cells going through mitosis undergo precisely timed changes in cell shape and
organisation, which serve to ensure the fair partitioning of cellular components into the two …

GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3

D Li, Y Yang, C Lv, Y Wang, X Chao, J Huang… - Journal of Cell …, 2023 - rupress.org
The actin-rich cortex plays a fundamental role in many cellular processes. Its architecture
and molecular composition vary across cell types and physiological states. The full …

A novel membrane anchor for FtsZ is linked to cell wall hydrolysis in Caulobacter crescentus

EL Meier, S Razavi, T Inoue… - Molecular microbiology, 2016 - Wiley Online Library
In most bacteria, the tubulin‐like GTPase FtsZ forms an annulus at midcell (the Z‐ring) which
recruits the division machinery and regulates cell wall remodeling. Although both activities …

How the mechanobiome drives cell behavior, viewed through the lens of control theory

P Kothari, C Johnson, C Sandone… - Journal of cell …, 2019 - journals.biologists.com
Cells have evolved sophisticated systems that integrate internal and external inputs to
coordinate cell shape changes during processes, such as development, cell identity …

The Cdc42 GTPase-activating protein Rga6 promotes the cortical localization of septin

S Zheng, B Zheng, Z Liu, X Ma, X Liu… - Journal of cell …, 2022 - journals.biologists.com
Septins are a family of filament-forming GTP-binding proteins that regulate fundamental
cellular activities, such as cytokinesis and cell polarity. In general, septin filaments function …

Scanning electrochemical microscopy of Belousov–Zhabotinsky reaction: How confined oscillations reveal short lived radicals and auto-catalytic species

TJ Stockmann, JM Noël, S Ristori… - Analytical …, 2015 - ACS Publications
Oscillating chemical reactions, encapsulated within artificial vesicles have been
demonstrated as a powerful analogy of living cells for the investigation of chemical …