Inflammation is part of innate immunity and is a natural response of the body to bacteria,
virus, and any other pathogen infections or to damaged tissues. However, too much …

The role of Cl–as an intracellular signaling ion has been increasingly recognized in recent
years. One of the currently best described roles of Cl–in signaling is the modulation of the W …

The molecular and cellular mechanisms underlying complex axon morphogenesis are still
poorly understood. We report a novel, evolutionary conserved function for the Drosophila …

Inherited painless neuropathies arise due to genetic insults that either block the normal
signaling of or destroy the sensory afferent neurons in the dorsal root ganglion (DRG) …

Inherited neuropathies are a heterogeneous group of slowly progressive disorders affecting
either motor, sensory, and/or autonomic nerves. Peripheral neuropathy may be the major …

With no lysine kinase 1 (WNK1) phosphorylates and activates STE20/SPS1-related proline-
alanine-rich protein kinase (SPAK) and oxidative stress responsive kinase 1 (OSR1) to …

Hereditary sensory and autonomic neuropathy type 2 (HSAN2) is a group of extremely rare
autosomal recessive neurological disorders characterized by predominant sensory …

Hereditary sensory and autonomic neuropathy (HSAN) is a rare genetic disorder that
primarily affects the peripheral nervous system, leading to a progressive loss of the ability to …

The autonomic nervous system (ANS) is responsible for functions of the body that are not
under conscious control, such as blood pressure, heart rate, bowel movements, and …

The maintenance of neuronal circuits is vital for sustaining nervous system function
throughout life. Neurons are particularly susceptible to damage from metabolic and …