There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Many of the medicinally active molecules in the flavonoid class of phytochemicals are being
researched for their potential antiviral activity against various DNA and RNA viruses …

The presented study was performed to verify whether rutin and/or quercetin can inhibit liver
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …

Sweet and bitter oranges are two of the most commercially-important fruit with a total world
production of 75.4 Mt, well-recognized for their unique sensory characters in addition to …

Hepatocellular carcinoma (HCC) has been identified as one of the most deadly
malignancies with limited therapeutic efficacy worldwide. However, understanding the …

Cyclophosphamide (CYCP), a synthetic alkylating antineoplastic, disrupts both cancerous
and non-cancerous cells to cause cancer regression and multi organotoxicity respectively …

Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

Citrus fruits processing results in the generation of huge amounts of citrus by-products,
mainly peels, pulp, membranes, and seeds. Although they represent a major concern from …

This study is aimed at evaluating the preventive effect and at suggesting the mode of actions
of naringin and hesperidin and their combination in diclofenac‐induced hepatotoxicity. Male …

Doxorubicin (Dox) is an operational and largely used anticancer drug, used to treat an array
of malignancies. Nonetheless, its beneficial use is constrained due to its renal and …