Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Early mast cell (MC) infiltration has been reported in a wide range of human and animal
tumors particularly malignant melanoma and breast and colorectal cancer. The …

Cells grown in vitro are dramatically perturbed by their new microenvironment. Analyses of
genome-wide gene expression levels offer a first glance at which genes and pathways are …

Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Mast cells in tissues are developed from mast cell progenitors emerging from the bone
marrow in a process highly regulated by transcription factors. Through the advancement of …

Recent genetic evidence has established a pathogenetic role for NF-κB signaling in cancer.
NF-κB signaling is engaged transiently when normal B lymphocytes respond to antigens, but …

Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …

Hodgkin's lymphoma (HL) represents the most common subtype of malignant lymphoma in
young people in the Western world. Most patients can be cured with modern treatment …

Mast cells accumulate in the stroma surrounding certain tumors, especially mammary
adenocarcinoma, and molecules they secrete could benefit the tumor. These include …

The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …