T cells in health and disease
L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
The IL-23/IL-17 pathway in inflammatory skin diseases: from bench to bedside
T Liu, S Li, S Ying, S Tang, Y Ding, Y Li, J Qiao… - Frontiers in …, 2020 - frontiersin.org
Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …
The role of TH17 cells in multiple sclerosis: Therapeutic implications
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
The role of immune cells and mediators in preeclampsia
E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
CAR-T cell performance: how to improve their persistence?
G López-Cantillo, C Urueña, BA Camacho… - Frontiers in …, 2022 - frontiersin.org
Adoptive cell therapy with T cells reprogrammed to express chimeric antigen receptors (CAR-
T cells) has been highly successful in patients with hematological neoplasms. However, its …
T cells) has been highly successful in patients with hematological neoplasms. However, its …
Immune mechanisms in oral lichen planus
A El‐Howati, MH Thornhill, HE Colley… - Oral diseases, 2023 - Wiley Online Library
Oral lichen planus (OLP) is a T cell‐mediated inflammatory disease of the oral mucosa that
has been extensively researched over many years but as yet the mechanisms of …
has been extensively researched over many years but as yet the mechanisms of …
Role of gut microbiota in infectious and inflammatory diseases
MF Maciel-Fiuza, GC Muller, DMS Campos… - Frontiers in …, 2023 - frontiersin.org
Thousands of microorganisms compose the human gut microbiota, fighting pathogens in
infectious diseases and inhibiting or inducing inflammation in different immunological …
infectious diseases and inhibiting or inducing inflammation in different immunological …
Key advances in vaccine development for tuberculosis—Success and challenges
Breakthrough findings in the clinical and preclinical development of tuberculosis (TB)
vaccines have galvanized the field and suggest, for the first time since the development of …
vaccines have galvanized the field and suggest, for the first time since the development of …
The role of Th17 cells in psoriasis
B Li, L Huang, P Lv, X Li, G Liu, Y Chen, Z Wang… - Immunologic …, 2020 - Springer
Abstract T helper 17 (Th17) cells have been involved in the pathogenesis of many
autoimmune and inflammatory diseases, like psoriasis, multiple sclerosis (MS), rheumatoid …
autoimmune and inflammatory diseases, like psoriasis, multiple sclerosis (MS), rheumatoid …
Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures
BACKGROUND Immune-related adverse events (irAEs) and their associated
morbidity/mortality are a key concern for patients receiving immune checkpoint inhibitors …
morbidity/mortality are a key concern for patients receiving immune checkpoint inhibitors …