Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

Chiral amino acids are extensively applied in the pharmaceutical, food, cosmetic,
agricultural, and feedstuff industries. The development of synthetic methodologies for …

Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

Multi‐enzymatic cascade reactions, ie, the combination of several enzymatic transformations
in concurrent one‐pot processes, offer considerable advantages: the demand of time, costs …

Microorganisms are a promising source of an enormous number of natural products, which
have made significant contribution to almost each sphere of human, plant and veterinary life …

Carrier-bound Immobilized Enzymes The first systematic overview of this key technique
since the early 1990s, this authoritative reference is the only handbook available to include …

Today, biocatalysis is a standard technology for the production of chemicals. An analysis of
134 industrial biotransformations reveals that hydrolases (44%) and redox biocatalysts …

Biocatalysis fulfils many key criteria of green chemistry, but this raises the question: how
efficient are such production methods and how important is biotechnology for greener …

NAD (P)-dependent oxidoreductases are valuable tools for the synthesis of chiral
compounds. Due to the high cost of the pyridine cofactors, in situ cofactor regeneration is …

Unnatural amino acids (UAAs) are valuable building blocks in the manufacture of a wide
range of pharmaceuticals. UAAs exhibit biological activity as free acids and they can be …