Genetic, parental and lifestyle factors influence telomere length

S Andreu-Sánchez, G Aubert… - Communications …, 2022 - nature.com
The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …

Utility of whole genome sequencing in assessing risk and clinically relevant outcomes for pulmonary fibrosis

D Zhang, CA Newton, B Wang… - European …, 2022 - publications.ersnet.org
Background Whole genome sequencing (WGS) can detect variants and estimate telomere
length. The clinical utility of WGS in estimating risk, progression and survival of pulmonary …

Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data

A Al Khleifat, A Iacoangeli, AR Jones… - Frontiers in cellular …, 2022 - frontiersin.org
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterized by the loss of upper and lower motor neurons, leading to progressive …

Telomeres are shorter in wild Saccharomyces cerevisiae isolates than in domesticated ones

M D'Angiolo, JX Yue, M De Chiara, BP Barré… - Genetics, 2023 - academic.oup.com
Telomeres are ribonucleoproteins that cap chromosome-ends and their DNA length is
controlled by counteracting elongation and shortening processes. The budding yeast …

Genetically inferred telomere length and testicular germ cell tumor risk

DW Brown, Q Lan, N Rothman, J Pluta… - Cancer Epidemiology …, 2021 - aacrjournals.org
Background: Studies evaluating the association between peripheral blood leukocyte
telomere length (LTL) and testicular germ cell tumor (TGCT) risk have produced conflicting …

Immune, metabolic, and microbial aspects of human health and aging

SA Sánchez - 2024 - research.rug.nl
Human disease is often associated with dysfunctions in the immune system or metabolism.
These dysfunctions are frequently linked to variations in the gut microbiome—the collection …

An investigation of genetically determined telomere length and its impact on disease in UK Biobank

S Stoma - 2021 - figshare.le.ac.uk
Telomere length has been proposed as a marker of biological age, and numerous studies
have shown associations between directly measured telomere length and age-related …

[PDF][PDF] Fellowships

DE Weeks - 2023 - publichealth.pitt.edu
1993 Lisa D. Harby, MS" A teratogen information service: profile of the patient caller and
development of a pregnancy outcome questionnaire" 1993 D. Andrew Merriwether, Ph. D." …