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Genetic, parental and lifestyle factors influence telomere length
S Andreu-Sánchez, G Aubert… - Communications …, 2022 - nature.com
The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …
Utility of whole genome sequencing in assessing risk and clinically relevant outcomes for pulmonary fibrosis
D Zhang, CA Newton, B Wang… - European …, 2022 - publications.ersnet.org
Background Whole genome sequencing (WGS) can detect variants and estimate telomere
length. The clinical utility of WGS in estimating risk, progression and survival of pulmonary …
length. The clinical utility of WGS in estimating risk, progression and survival of pulmonary …
Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
characterized by the loss of upper and lower motor neurons, leading to progressive …
characterized by the loss of upper and lower motor neurons, leading to progressive …
Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes
Telomeres are DNA-protein structures at the ends of chromosomes essential in maintaining
chromosomal stability. Observational studies have identified associations between …
chromosomal stability. Observational studies have identified associations between …
Telomeres are shorter in wild Saccharomyces cerevisiae isolates than in domesticated ones
Telomeres are ribonucleoproteins that cap chromosome-ends and their DNA length is
controlled by counteracting elongation and shortening processes. The budding yeast …
controlled by counteracting elongation and shortening processes. The budding yeast …
Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential
Human genetic studies support an inverse causal relationship between leukocyte telomere
length (LTL) and coronary artery disease (CAD), but directionally mixed effects for LTL and …
length (LTL) and coronary artery disease (CAD), but directionally mixed effects for LTL and …
Genetically inferred telomere length and testicular germ cell tumor risk
Background: Studies evaluating the association between peripheral blood leukocyte
telomere length (LTL) and testicular germ cell tumor (TGCT) risk have produced conflicting …
telomere length (LTL) and testicular germ cell tumor (TGCT) risk have produced conflicting …
Immune, metabolic, and microbial aspects of human health and aging
SA Sánchez - 2024 - research.rug.nl
Human disease is often associated with dysfunctions in the immune system or metabolism.
These dysfunctions are frequently linked to variations in the gut microbiome—the collection …
These dysfunctions are frequently linked to variations in the gut microbiome—the collection …
An investigation of genetically determined telomere length and its impact on disease in UK Biobank
S Stoma - 2021 - figshare.le.ac.uk
Telomere length has been proposed as a marker of biological age, and numerous studies
have shown associations between directly measured telomere length and age-related …
have shown associations between directly measured telomere length and age-related …
[PDF][PDF] Fellowships
DE Weeks - 2023 - publichealth.pitt.edu
1993 Lisa D. Harby, MS" A teratogen information service: profile of the patient caller and
development of a pregnancy outcome questionnaire" 1993 D. Andrew Merriwether, Ph. D." …
development of a pregnancy outcome questionnaire" 1993 D. Andrew Merriwether, Ph. D." …