B cell leukaemia is one of the most frequent malignancies in the paediatric population, but
also affects a significant proportion of adults in developed countries. The majority of infant …

Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. ALL arises
from the malignant transformation of progenitor B-and T-cells in the bone marrow into …

Genomic landscapes of 92 adult and 111 pediatric patients with B-cell acute lymphoblastic
leukemia (B-ALL) were investigated using next-generation sequencing and copy number …

We report a systematic analysis of the DNA methylation variability in 1,595 samples of
normal cell subpopulations and 14 tumor subtypes spanning the entire human B-cell …

Background Maternal blood pressure levels reflect cardiovascular adaptation to pregnancy
and proper maternal-fetal exchanges through the placenta and are very sensitive to …

The identification and study of genetic alterations involved in various signaling pathways
associated with the pathogenesis of acute lymphoblastic leukemia (ALL) and the application …

Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia
(BCP-ALL) carries an immunoglobulin-MYC rearrangement (IG-MYC-r). This can result in …

Identification of body fluid stain at crime scene is one of the important tasks of forensic
evidence analysis. Currently, body fluid-specific CpGs detected by DNA methylation …

Acute lymphoblastic leukemia (ALL) is one of the commonest hematological malignancies
affecting children and adults. Recent evidence suggests an involvement of Epstein-Barr …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. It is well-known
that genetic alterations constitute the basis for the etiology of ALL. However, genetic …