Cellular responses to TNF are inherently heterogeneous within an isogenic cell population
and across different cell types. TNF promotes cell survival by activating pro-inflammatory NF …

Sepsis involves the dynamic interplay between a pathogen, the host response, the failure of
organ systems, medical interventions and a myriad of other factors. This together results in a …

A new 4D chaotic system with self-excited attractors or hidden attractors is designed and the
generation of self-excited attractors and hidden attractors depends on the parameters of the …

Recent advances in single-cell sequencing technologies have provided unprecedented
opportunities to measure the gene expression profile and RNA velocity of individual cells …

Chaos, or exponential sensitivity to small perturbations, appears everywhere in nature.
Moreover, chaos is predicted to play diverse functional roles in living systems. A method for …

Living organisms are constantly exposed to DNA damage, and optimal repair is therefore
crucial. A characteristic hallmark of the response is the formation of sub-compartments …

Cellular responses to environmental changes are often highly heterogeneous and exhibit
seemingly random dynamics. The astonishing insight of chaos theory is that such …

Oscillations are a recurrent phenomenon in biological systems across scales, but
deciphering their fundamental principles is very challenging. Here, we tackle this challenge …

Abstract Yes-associated protein 1 (YAP) is a transcriptional regulator with critical roles in
mechanotransduction, organ size control, and regeneration. Here, using advanced tools for …

The discovery of structure from time series data is a key problem in fields of study working
with complex systems. Most identifiability results and learning algorithms assume the …