The key players of the chronic kidney disease-mineral and bone disorders (CKD-MBD) are
calcium, phosphate, PTH, FGF23, and the vitamin D hormonal system. The progressive …

The association between vitamin D deficiency and especially critical shortage of active
vitamin D (1, 25-dihydroxyvitamin D, calcitriol) with the development of secondary …

Importance Secondary hyperparathyroidism contributes to extraskeletal calcification and is
associated with all-cause and cardiovascular mortality. Control is suboptimal in the majority …

Intradialytic hypotension (IDH) is the most common acute complication in hemodialysis (HD)
sessions and is associated with increased morbidity and mortality in HD patients. To prevent …

Hyperphosphatemia has consistently been shown to be associated with dismal outcome in a
wide variety of populations, particularly in chronic kidney disease (CKD). Compelling …

The extracellular domain of transmembrane alpha-Klotho (αKlotho, hereinafter simply called
Klotho) is cleaved by secretases and released into the circulation as soluble Klotho. Soluble …

Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney
disease (CKD). Multiple factors account for the increased incidence of cardiovascular …

The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline
Update for the Diagnosis, Evaluation, Prevention, and Treatment of chronic kidney disease …

As in 2011, when the Spanish Society of Nephrology (SEN) published the Spanish
adaptation to the Kidney Disease: Improving Global Outcomes (KDIGO) universal Guideline …

Methods In a single-arm, open-label, 36-week prospective trial, we hypothesized that
etelcalcetide improves bone quality and strength without damaging bone–tissue quality …