There is a great interest to develop co-amorphous drug delivery systems to enhance the
solubility of biopharmaceutics classification system (BCS) class II and IV drugs. However …

Rheumatoid arthritis (RA) is a chronic autoimmune joint disorder that affects about 1% of the
world population and may lead to severe disability and comorbidity. Despite breakthroughs …

There is strong interest to develop affordable treatments for the infection-associated
rheumatoid arthritis (RA). Here, we present a drug–drug co-amorphous strategy against RA …

Sinomenine (SIN), isolated from Caulis sinomenii, is a benzyltetrahydroisoquinoline-type
alkaloid with potent anti-inflammatory and analgesic effects. SIN-HCl has been used in the …

Sulfathiazole forms II, III and IV are polytypes where common monolayers accumulate in
different stacking modes. These polytypes are difficult to identify using conventional …

Matrine (MAT) is a natural tetracyclo-quinolizidine alkaloid with various pharmacological
activities. Due to its excessive solubility, oral administration of MAT exhibits rapid absorption …

A Fourier transform infrared (FTIR) experiment appropriate for an upper-level undergraduate
laboratory such as chemical instrumentation is described. Students collect FTIR spectra of …

Resveratrol (RSV) is one of the most extensively investigated natural polyphenol with
potential cardioprotective effects and various biological activities. However, the …

High drug cargo loading in polymer and physical stability was essential for the development
of orodispersible films (ODFs) because of the small amount of excipients used in a thin film …

Discrimination of active pharmaceutical ingredients (APIs) existing as neutral molecules or
salts is essential and complicated. However, the discrimination of pharmaceutical salts by …