Spice oleoresins as value-added ingredient for food industry: Recent advances and perspectives.

FR Procopio, MC Ferraz, BN Paulino… - Trends in Food Science …, 2022 - Elsevier
Background Oleoresins are concentrated extracts from plants, spices, and herbs which have
been studied as additives in foods. Extracted from natural sources by different techniques …

Dual BET/HDAC inhibition to relieve neuropathic pain: recent advances, perspectives, and future opportunities

MN Romanelli, V Borgonetti, N Galeotti - Pharmacological Research, 2021 - Elsevier
Despite the intense research on develo** new therapies for neuropathic pain states,
available treatments have limited efficacy and unfavorable safety profiles. Epigenetic …

[HTML][HTML] Ylang-ylang (Cananga odorata (Lam.) Hook. f. & Thomson) essential oil reduced neuropathic-pain and associated anxiety symptoms in mice

V Borgonetti, V López, N Galeotti - Journal of ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Ylang-ylang essential oil (YEO), obtained from the flowers
of the tropical tree Cananga odorata (Lam.) Hook. f. & Thomson (family Annonaceae), has …

SIRT3‐mediated CypD‐K166 deacetylation alleviates neuropathic pain by improving mitochondrial dysfunction and inhibiting oxidative stress

B Yan, Q Liu, X Ding, Y Lin, X Jiao, Y Wu… - Oxidative Medicine …, 2022 - Wiley Online Library
Numerous studies have shown that mitochondrial dysfunction manifested by increased
mitochondrial permeability transition pore (mPTP) opening and reactive oxygen species …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

[HTML][HTML] Zingiberene, a non-zinc-binding class I HDAC inhibitor: A novel strategy for the management of neuropathic pain

V Borgonetti, P Governa, F Manetti, N Galeotti - Phytomedicine, 2023 - Elsevier
Abstract Background Even though numerous Histone deacetylase inhibitors (HDACi) have
been approved for the treatment of different types of cancer, and others are in clinical trials …

Dietary supplementation of gingerols-and shogaols-enriched ginger root extract attenuate pain-associated behaviors while modulating gut microbiota and metabolites …

CL Shen, R Wang, G Ji, MM Elmassry… - The Journal of nutritional …, 2022 - Elsevier
Neuroinflammation is a central factor in neuropathic pain (NP). Ginger is a promising
bioactive compound in NP management due to its anti-inflammatory property. Emerging …

A systematic review and meta-analysis on the role of Nutraceuticals in the management of neuropathic pain in in vivo studies

S Ilari, S Proietti, P Russo, V Malafoglia, M Gliozzi… - Antioxidants, 2022 - mdpi.com
The control of neuropathic pain is a leading challenge in modern medicine. Traditional
medicine has, for a long time, used natural compounds such as nutraceuticals for this …

Bioactive compounds for neuropathic pain: An update on preclinical studies and future perspectives

CL Shen, L Castro, CY Fang, M Castro… - The Journal of …, 2022 - Elsevier
Among different types of chronic pain, neuropathic pain (NP), arising from damage to the
nervous system, including peripheral fibers and central neurons, is notoriously difficult to …

Ginger (Zingiber officinale) Root Capsules Enhance Analgesic and Antioxidant Efficacy of Diclofenac Sodium in Experimental Acute Inflammation

I Boarescu, RM Pop, PM Boarescu, IC Bocșan… - Antioxidants, 2023 - mdpi.com
Our study aimed to evaluate the analgesic and antioxidant effects of ginger (Zingiber
officinale) root capsule extract (GRCE) in addition to diclofenac (D) sodium treatment in …