Toll‐like receptor polymorphism in host immune response to infectious diseases: A review

S Mukherjee, S Huda… - Scandinavian journal of …, 2019 - Wiley Online Library
Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …

The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses

AK Gupta, S Das, M Kamran, SA Ejazi, N Ali - Virulence, 2022 - Taylor & Francis
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

Toll‐Like Receptors in Leishmania Infections: Guardians or Promoters?

MS Faria, FCG Reis, APCA Lima - Journal of parasitology …, 2012 - Wiley Online Library
Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease

VR Villella, A Venerando, G Cozza, S Esposito… - The EMBO …, 2019 - embopress.org
Intestinal handling of dietary proteins usually prevents local inflammatory and immune
responses and promotes oral tolerance. However, in~ 1% of the world population, gluten …

Redundant and regulatory roles for Toll-like receptors in Leishmania infection

P Chauhan, D Shukla… - Clinical & …, 2017 - academic.oup.com
Toll-like receptors (TLRs) are germline-encoded, non-clonal innate immune receptors,
which are often the first receptors to recognize the molecular patterns on pathogens …

Leishmania braziliensis Infection Enhances Toll-Like Receptors 2 and 4 Expression and Triggers TNF-α and IL-10 Production in Human Cutaneous Leishmaniasis

LP Polari, PP Carneiro, M Macedo… - Frontiers in cellular …, 2019 - frontiersin.org
Cutaneous leishmaniasis (CL) caused by infection with Leishmania braziliensis is
characterized by an exaggerated inflammatory response that controls the parasite burden …

Neutrophils and Visceral Leishmaniasis: Impact on innate immune response and cross‐talks with macrophages and dendritic cells

M Kupani, RK Pandey… - Journal of Cellular …, 2021 - Wiley Online Library
Neutrophils with their array of microbicidal activities are the first innate immune cells to
guard against infection. They are also most crucial for the host's initial defense against …

Transcription of Toll-Like Receptors 2, 3, 4 and 9, FoxP3 and Th17 Cytokines in a Susceptible Experimental Model of Canine Leishmania infantum Infection

S Hosein, A Rodriguez-Cortes, DP Blake… - PloS one, 2015 - journals.plos.org
Canine leishmaniosis (CanL) due to Leishmania infantum is a chronic zoonotic systemic
disease resulting from complex interactions between protozoa and the canine immune …

Regulatory actions of Toll-like receptor 2 (TLR2) and TLR4 in Leishmania donovani infection in the liver

HW Murray, Y Zhang, Y Zhang, VS Raman… - Infection and …, 2013 - Am Soc Microbiol
In livers of susceptible but self-curing C57BL/6 mice, intracellular Leishmania donovani
infection enhanced Toll-like receptor 4 (TLR4) and TLR2 gene expression. In the liver …