Ketamine is a promising therapeutic option in treatment-resistant depression (TRD). The
acute efficacy of ketamine in TRD has been demonstrated in replicated randomised …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Importance Whether ketamine is as effective as electroconvulsive therapy (ECT) among
patients with major depressive episode remains unknown. Objective To systematically …

Background ECT is considered the fastest and most effective treatment for TRD. Ketamine
seems to be an attractive alternative due to its rapid-onset antidepressant effects and impact …

We conducted a systematic review and meta-analysis to investigate the comparative
effectiveness of ketamine versus electroconvulsive therapy (ECT) for the treatment of major …

Background Ketamine and its enantiomer have rapid and robust effects on depressive
symptom and suicidal ideation. Little is known about their cognitive effects in adolescents …

Intravenous (IV) subanesthetic doses of ketamine have been shown to reduce psychiatric
distress in both major depressive (MDD) and posttraumatic stress disorder (PTSD) …

Eating disorders (EDs) are serious, life-threatening psychiatric conditions associated with
physical and psychosocial impairment, as well as high morbidity and mortality. Given the …

Abstract Background: Treatment-Resistant Depression (TRD) challenges psychiatric
treatment, with existing guidelines covering only a subset of augmentation strategies …

Depression is a leading cause of disability globally, with a prevalence of 3.8% among the
whole population, 5% of the adult population, and 5.7% of the elderly population over 60 …