The Genome of the Kinetoplastid Parasite, Leishmania major
Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
Gene expression in trypanosomatid parasites
The parasites Leishmania spp., Trypanosoma brucei, and Trypanosoma cruzi are the
trypanosomatid protozoa that cause the deadly human diseases leishmaniasis, African …
trypanosomatid protozoa that cause the deadly human diseases leishmaniasis, African …
Comparative genomics of trypanosomatid parasitic protozoa
A comparison of gene content and genome architecture of Trypanosoma brucei,
Trypanosoma cruzi, and Leishmania major, three related pathogens with different life cycles …
Trypanosoma cruzi, and Leishmania major, three related pathogens with different life cycles …
Operons in eukaryotes
T Blumenthal - Briefings in Functional Genomics, 2004 - academic.oup.com
It was thought that polycistronic transcription is a characteristic of bacteria and archaea,
where many of the genes are clustered in operons composed of two to more than ten genes …
where many of the genes are clustered in operons composed of two to more than ten genes …
The Trypanosoma cruzi Proteome
JA Atwood III, DB Weatherly, TA Minning, B Bundy… - Science, 2005 - science.org
To complement the sequencing of the three kinetoplastid genomes reported in this issue, we
have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of …
have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of …
Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi
Background Due to the absence of transcription initiation regulation of protein coding genes
transcribed by RNA polymerase II, posttranscriptional regulation is responsible for the …
transcribed by RNA polymerase II, posttranscriptional regulation is responsible for the …
Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages: the Leishmania genome is constitutively expressed
Leishmania are protozoan parasites that cause a wide spectrum of clinical diseases in
humans and are a major public health risk in several countries. Leishmania life cycle …
humans and are a major public health risk in several countries. Leishmania life cycle …
[HTML][HTML] Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania
HGAM van Luenen, C Farris, S Jan, PA Genest… - Cell, 2012 - cell.com
Some Ts in nuclear DNA of trypanosomes and Leishmania are hydroxylated and
glucosylated to yield base J (β-D-glucosyl-hydroxymethyluracil). In Leishmania, about 99 …
glucosylated to yield base J (β-D-glucosyl-hydroxymethyluracil). In Leishmania, about 99 …
From Stop to Start: Tandem Gene Arrangement, Copy Number and Trans-Splicing Sites in the Dinoflagellate Amphidinium carterae
Dinoflagellate genomes present unique challenges including large size, modified DNA
bases, lack of nucleosomes, and condensed chromosomes. EST sequencing has shown …
bases, lack of nucleosomes, and condensed chromosomes. EST sequencing has shown …
Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation
A Saxena, T Lahav, N Holland, G Aggarwal… - Molecular and …, 2007 - Elsevier
Leishmania donovani is an intracellular protozoan parasite that causes kala-azar in
humans. During infection the extracellular insect forms (promastigotes) undergo rapid …
humans. During infection the extracellular insect forms (promastigotes) undergo rapid …