Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

The purpose of this paper is to evaluate the ability of a prototype Compton camera (CC) to
measure prompt gamma rays (PG) emitted during delivery of clinical proton pencil beams for …

Ion beam therapy promises enhanced tumour coverage compared to conventional
radiotherapy, but particle range uncertainties significantly blunt the achievable precision …

In proton therapy, patients benefit from the precise deposition of the dose in the tumor
volume due to the interaction of charged particles with matter. Currently, the determination of …

Objective. In this study we introduce spatiotemporal emission reconstruction prompt gamma
timing (SER-PGT), a new method to directly reconstruct the prompt photon emission in the …

Proton beams are promising means for treating tumors. Such charged particles stop at a
defined depth, where the ionization density is maximum. As the dose deposit beyond this …

We present the results of an investigation of the prompt-gamma emission from an interaction
of a proton beam with phantom materials. Measurements were conducted with a novel setup …

The only method for in vivo dose delivery verification in proton beam radiotherapy in clinical
use today is positron emission tomography (PET) of the positron emitters produced in the …