Hyaluronic acid: redefining its role

G Abatangelo, V Vindigni, G Avruscio, L Pandis, P Brun - Cells, 2020 - mdpi.com
The discovery of several unexpected complex biological roles of hyaluronic acid (HA) has
promoted new research impetus for biologists and, the clinical interest in several fields of …

Flow behavior prior to crosslinking: The need for precursor rheology for placement of hydrogels in medical applications and for 3D bioprinting

JM Townsend, EC Beck, SH Gehrke… - Progress in polymer …, 2019 - Elsevier
Hydrogels–water swollen crosslinked networks–have demonstrated considerable promise
in tissue engineering and regenerative medicine applications. However, ambiguity over …

[HTML][HTML] Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management

J Wen, H Li, H Dai, S Hua, X Long, H Li, S Ivanovski… - Materials Today Bio, 2023 - Elsevier
Osteoarthritis (OA) and rheumatoid arthritis (RA) are chronic and progressive inflammatory
joint diseases that affect a large population worldwide. Intra-articular administration of …

The role of hyaluronic acid in cartilage boundary lubrication

W Lin, Z Liu, N Kampf, J Klein - Cells, 2020 - mdpi.com
Hydration lubrication has emerged as a new paradigm for lubrication in aqueous and
biological media, accounting especially for the extremely low friction (friction coefficients …

Therapeutic hydrogel sheets programmed with multistage drug delivery for effective treatment of corneal abrasion

LJ Luo, DD Nguyen, CC Huang, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Corneal abrasion (CA) is a leading cause of inflammation, scar formation, and even loss of
vision in the eye if allowed to progress; however, current treatments remain constrained by …

Hyaluronic acid hydrophilic surface rehabilitating curcumin nanocrystals for targeted breast cancer treatment with prolonged biodistribution

P Ji, L Wang, Y Chen, S Wang, Z Wu, X Qi - Biomaterials science, 2020 - pubs.rsc.org
Due to its high therapeutic efficiency and low systemic toxicity, natural bioactive curcumin
has attracted more and more attention as a potential antineoplastic drug. Although the …

Self-healing dynamic hydrogel as injectable shock-absorbing artificial nucleus pulposus

A Pérez-San Vicente, M Peroglio, M Ernst… - …, 2017 - ACS Publications
The intervertebral discs (IVDs) provide unique flexibility to the spine and exceptional shock
absorbing properties under impact. The inner core of the IVD, the nucleus pulposus (NP) is …

Saturated fatty acid-based in situ forming matrices for localized antimicrobial delivery

T Chantadee, W Santimaleeworagun, Y Phorom… - Pharmaceutics, 2020 - mdpi.com
In recent years, the world has faced the issue of antibiotic resistance. Methicillin-resistant
Staphylococcus aureus (MRSA) is a significant problem in various treatments and control of …

Effect of molecular weight of hyaluronic acid (HA) on viscoelasticity and particle texturing feel of HA dermal biphasic fillers

C Chun, DY Lee, JT Kim, MK Kwon, YZ Kim… - Biomaterials …, 2016 - spj.science.org
Background Hyaluronic acid (HA) dermal biphasic fillers are synthesized for their efficacy in
correcting aesthetic defects such as wrinkles, scars and facial contouring defects. The fillers …

Bioinspired synthesis of bioactive glass nanocomposites for hyaluronic acid delivery to bone and skin

N Dey, FP Mohny, GB Reshma, D Rao… - International Journal of …, 2023 - Elsevier
In this study, we present nanocomposites of bioactive glass (BG) and hyaluronic acid
(HA)(nano-BGHA) for effective delivery of HA to skin and bone. The synthesis of the …