The “1000Genome”projecthasbeendrawingincreasingattention….Nanoporesequencing,
thethird-generation,isbelievedtobeoneofthemostpromisingsequ…“ 1000 Genome” while the …

Nanopores are being hailed as a potential next-generation DNA sequencer that could
provide cheap, high-throughput DNA analysis. In this review we present a detailed summary …

The chemical nature and precise position of posttranslational modifications (PTMs) in
proteins or peptides are crucial for various severe diseases, such as cancer. State-of-the-art …

DNA sequencing by synthesis (SBS) offers a robust platform to decipher nucleic acid
sequences. Recently, we reported a single-molecule nanopore-based SBS strategy that …

the de novo base calling of an organism at the Advances in Genome Biology and
Technology conference (AGBT; Marco Island, FL, USA) 7 with read lengths in excess of 50 …

The synergy of life sciences discoveries, biomolecular and protein engineering advances,
and groundbreaking nanofabrication technologies, has introduced over the past years the …

Summary The Human Genome Project opened an era of (epi) genomic research, and also
provided a platform for the development of new sequencing technologies. During and after …

Ion transport through nanopores permeates through many areas of science and technology,
from cell behavior to sensing and separation to catalysis and batteries. Two-dimensional …

The DNA origami technique can enable functionalization of inorganic structures for single-
molecule electric current recordings. Experiments have shown that several layers of DNA …

Proteinaceous nanometer-scale pores are ubiquitous in biology. The canonical ionic
channels (eg, those that transport Na+, K+, Ca 2+, and Cl− across cell membranes) play key …