New insights into the regulation of plant immunity by amino acid metabolic pathways

J Zeier - Plant, Cell & Environment, 2013 - Wiley Online Library
Besides defence pathways regulated by classical stress hormones, distinct amino acid
metabolic pathways constitute integral parts of the plant immune system. Mutations in …

Biocatalytic imine reduction and reductive amination of ketones

JH Schrittwieser, S Velikogne… - Advanced Synthesis & …, 2015 - Wiley Online Library
Chiral amines represent a prominent functional group in pharmaceuticals and
agrochemicals and are hence attractive targets for asymmetric synthesis. Since the …

Crym-positive striatal astrocytes gate perseverative behaviour

M Ollivier, JS Soto, KE Linker, SL Moye… - Nature, 2024 - nature.com
Astrocytes are heterogeneous glial cells of the central nervous system,–. However, the
physiological relevance of astrocyte diversity for neural circuits and behaviour remains …

Biochemical principles and functional aspects of pipecolic acid biosynthesis in plant immunity

M Hartmann, D Kim, F Bernsdorff… - Plant …, 2017 - academic.oup.com
The nonprotein amino acid pipecolic acid (Pip) regulates plant systemic acquired resistance
and basal immunity to bacterial pathogen infection. In Arabidopsis (Arabidopsis thaliana) …

l‐lysine metabolism to N‐hydroxypipecolic acid: an integral immune‐activating pathway in plants

M Hartmann, J Zeier - The Plant Journal, 2018 - Wiley Online Library
Summary l‐lysine catabolic routes in plants include the saccharopine pathway to α‐
aminoadipate and decarboxylation of lysine to cadaverine. The current review will cover a …

Lysine metabolism in mammalian brain: an update on the importance of recent discoveries

A Hallen, JF Jamie, AJL Cooper - Amino acids, 2013 - Springer
The lysine catabolism pathway differs in adult mammalian brain from that in extracerebral
tissues. The saccharopine pathway is the predominant lysine degradative pathway in …

The human crystallin gene families

G Wistow - Human genomics, 2012 - Springer
Crystallins are the abundant, long-lived proteins of the eye lens. The major human
crystallins belong to two different superfamilies: the small heat-shock proteins (α-crystallins) …

A NADPH-dependent (S)-imine reductase (SIR) from Streptomyces sp. GF3546 for asymmetric synthesis of optically active amines: purification, characterization …

K Mitsukura, T Kuramoto, T Yoshida, N Kimoto… - Applied microbiology …, 2013 - Springer
Abstract A NADPH-dependent (S)-imine reductase (SIR) was purified to be homogeneous
from the cell-free extract of Streptomyces sp. GF3546. SIR appeared to be a homodimer …

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

S Zhao, A Sakai, X Zhang, MW Vetting, R Kumar… - Elife, 2014 - elifesciences.org
Metabolic pathways in eubacteria and archaea often are encoded by operons and/or gene
clusters (genome neighborhoods) that provide important clues for assignment of both …

Biocatalytic synthesis of chiral N‐functionalized amino acids

JF Hyslop, SL Lovelock, PW Sutton… - Angewandte …, 2018 - Wiley Online Library
N‐Functionalized amino acids are important building blocks for the preparation of diverse
bioactive molecules, including peptides. The development of sustainable manufacturing …