Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …
Pathophysiology of CD4+ T-cell depletion in HIV-1 and HIV-2 infections
The hall mark of human immunodeficiency virus (HIV) infection is a gradual loss of CD4+ T-
cells and imbalance in CD4+ T-cell homeostasis, with progressive impairment of immunity …
cells and imbalance in CD4+ T-cell homeostasis, with progressive impairment of immunity …
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
B Jacquelin, V Mayau, B Targat… - The Journal of …, 2009 - Am Soc Clin Investig
African green monkeys (AGMs) infected with the AGM type of SIV (SIVagm) do not develop
chronic immune activation and AIDS, despite viral loads similar to those detected in humans …
chronic immune activation and AIDS, despite viral loads similar to those detected in humans …
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
C Kornfeld, MJY Ploquin, I Pandrea… - The Journal of …, 2005 - Am Soc Clin Investig
T cell activation levels in HIV infection are predictive of AIDS progression. We searched for
the immunological correlates of protection against disease progression by studying the early …
the immunological correlates of protection against disease progression by studying the early …
Systemic effects of inflammation on health during chronic HIV infection
Combination antiretroviral therapy for HIV infection improves immune function and
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
eliminates the risk of AIDS-related complications but does not restore full health. HIV …
CD4+ T‐cell depletion in HIV infection: mechanisms of immunological failure
The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive
depletion of CD 4+ T‐cell populations in close association with progressive impairment of …
depletion of CD 4+ T‐cell populations in close association with progressive impairment of …
The activation of bystander CD8+ T cells and their roles in viral infection
During viral infections, significant numbers of T cells are activated in a T cell receptor-
independent and cytokine-dependent manner, a phenomenon referred to as “bystander …
independent and cytokine-dependent manner, a phenomenon referred to as “bystander …
Sharing CD4+ T cell loss: when COVID-19 and HIV collide on immune system
COVID-19 is a distinctive infection characterized by elevated inter-human transmission and
presenting from absence of symptoms to severe cytokine storm that can lead to dismal …
presenting from absence of symptoms to severe cytokine storm that can lead to dismal …
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism
Progressive HIV infection is characterized by dysregulation of the intestinal immune barrier,
translocation of immunostimulatory microbial products, and chronic systemic inflammation …
translocation of immunostimulatory microbial products, and chronic systemic inflammation …
Plasma levels of soluble CD14 independently predict mortality in HIV infection
NG Sandler, H Wand, A Roque, M Law… - Journal of Infectious …, 2011 - academic.oup.com
Background. Chronic human immunodeficiency virus (HIV) infection is associated with
intestinal permeability and microbial translocation that contributes to systemic immune …
intestinal permeability and microbial translocation that contributes to systemic immune …