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Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity
BA Baldo - Archives of toxicology, 2021 - Springer
Opioid-induced respiratory depression is potentially life-threatening and often regarded as
the main hazard of opioid use. Main cause of death is cardiorespiratory arrest with hypoxia …
the main hazard of opioid use. Main cause of death is cardiorespiratory arrest with hypoxia …
The serotonin syndrome: from molecular mechanisms to clinical practice
J Francescangeli, K Karamchandani, M Powell… - International journal of …, 2019 - mdpi.com
The serotonin syndrome is a medication-induced condition resulting from serotonergic
hyperactivity, usually involving antidepressant medications. As the number of patients …
hyperactivity, usually involving antidepressant medications. As the number of patients …
The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity
Background: There are difficulties with the diagnosis of serotonin toxicity, particularly with
the use of Sternbach's criteria. Aim: To improve the criteria for diagnosing clinically …
the use of Sternbach's criteria. Aim: To improve the criteria for diagnosing clinically …
Serotonin syndrome: a brief review
Une version française de cet article est disponible sur le site www. jamc. ca elevated
transaminase levels or lower bicarbonate levels have been reported. 2, 3, 8 Disseminated …
transaminase levels or lower bicarbonate levels have been reported. 2, 3, 8 Disseminated …
Opioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
BA Baldo - Archives of toxicology, 2018 - Springer
Drugs may cause serotonin toxicity by a number of different mechanisms including inhibition
of serotonin uptake and metabolism, increased serotonin synthesis and release, activation …
of serotonin uptake and metabolism, increased serotonin synthesis and release, activation …
[책][B] Drug-induced diseases: prevention, detection, and management
JE Tisdale, DA Miller - 2010 - books.google.com
According to the authors, a drug-induced disease as an unintended effect of a drug, which
results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical …
results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical …
[PDF][PDF] Serotonin toxicity: a practical approach to diagnosis and treatment
Excess serotonin in the central nervous system leads to a condition commonly referred to as
the serotonin syndrome, but better described as a spectrum of toxicity—serotonin toxicity.• …
the serotonin syndrome, but better described as a spectrum of toxicity—serotonin toxicity.• …
The serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes
Introduction Serotonin syndrome (toxicity) describes adverse drug effects from toxic amounts
of intra-synaptic central nervous system serotonin. A wide range of drugs have been …
of intra-synaptic central nervous system serotonin. A wide range of drugs have been …
The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment
Serotonin toxicity (or serotonin syndrome) has become an increasingly common and
important clinical problem in medicine over the last 15 years with the introduction of many …
important clinical problem in medicine over the last 15 years with the introduction of many …
Conundrums in neurology: diagnosing serotonin syndrome–a meta-analysis of cases
Background Serotonin syndrome is a toxic state, caused by serotonin (5HT) excess in the
central nervous system. Serotonin syndrome's main feature is neuro-muscular …
central nervous system. Serotonin syndrome's main feature is neuro-muscular …