Antitumour dendritic cell vaccination in a priming and boosting approach

A Harari, M Graciotti, M Bassani-Sternberg… - Nature Reviews Drug …, 2020 - nature.com
Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …

Dendritic cell-based immunotherapy

RL Sabado, S Balan, N Bhardwaj - Cell research, 2017 - nature.com
Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …

A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy

C Liu, X Liu, X **ang, X Pang, S Chen, Y Zhang… - Nature …, 2022 - nature.com
The strategy of combining a vaccine with immune checkpoint inhibitors has been widely
investigated in cancer management, but the complete response rate for this strategy is still …

Dendritic cell–based cancer vaccines

PM Santos, LH Butterfield - The Journal of Immunology, 2018 - journals.aai.org
Dendritic cells (DC) are specialized immune cells that play a critical role in promoting an
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …

Vitiligo-like depigmentation in patients with stage III-IV melanoma receiving immunotherapy and its association with survival: a systematic review and meta-analysis

HE Teulings, J Limpens, SN Jansen… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Vitiligo-like depigmentation in patients with melanoma may be associated with
more favorable clinical outcome. We conducted a systematic review of patients with stage III …

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

DA Mitchell, KA Batich, MD Gunn, MN Huang… - Nature, 2015 - nature.com
After stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce
immune responses. As such, autologous DCs generated ex vivo have been pulsed with …

Cancer immunotherapy via dendritic cells

K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
Cancer immunotherapy attempts to harness the power and specificity of the immune system
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …

Therapeutic cancer vaccines: past, present, and future

C Guo, MH Manjili, JR Subjeck, D Sarkar… - Advances in cancer …, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …

Personalized dendritic cell vaccines—recent breakthroughs and encouraging clinical results

B Mastelic-Gavillet, K Balint, C Boudousquie… - Frontiers in …, 2019 - frontiersin.org
With the advent of combined immunotherapies, personalized dendritic cell (DC)-based
vaccination could integrate the current standard of care for the treatment of a large variety of …

Taking dendritic cells into medicine

RM Steinman, J Banchereau - Nature, 2007 - nature.com
Dendritic cells (DCs) orchestrate a repertoire of immune responses that bring about
resistance to infection and silencing or tolerance to self. In the settings of infection and …