Antitumour dendritic cell vaccination in a priming and boosting approach
Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …
anticancer strategy but has not yet provided robust clinical benefits in large patient …
Dendritic cell-based immunotherapy
RL Sabado, S Balan, N Bhardwaj - Cell research, 2017 - nature.com
Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …
harnessing the potential of a patient's own immune system to eliminate tumor cells in …
A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy
C Liu, X Liu, X **ang, X Pang, S Chen, Y Zhang… - Nature …, 2022 - nature.com
The strategy of combining a vaccine with immune checkpoint inhibitors has been widely
investigated in cancer management, but the complete response rate for this strategy is still …
investigated in cancer management, but the complete response rate for this strategy is still …
Dendritic cell–based cancer vaccines
PM Santos, LH Butterfield - The Journal of Immunology, 2018 - journals.aai.org
Dendritic cells (DC) are specialized immune cells that play a critical role in promoting an
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …
immune response against Ags, which can include foreign pathogenic Ags and self-tumor …
Vitiligo-like depigmentation in patients with stage III-IV melanoma receiving immunotherapy and its association with survival: a systematic review and meta-analysis
HE Teulings, J Limpens, SN Jansen… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Vitiligo-like depigmentation in patients with melanoma may be associated with
more favorable clinical outcome. We conducted a systematic review of patients with stage III …
more favorable clinical outcome. We conducted a systematic review of patients with stage III …
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
After stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce
immune responses. As such, autologous DCs generated ex vivo have been pulsed with …
immune responses. As such, autologous DCs generated ex vivo have been pulsed with …
Cancer immunotherapy via dendritic cells
K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
Cancer immunotherapy attempts to harness the power and specificity of the immune system
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …
Therapeutic cancer vaccines: past, present, and future
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …
to treat late stage disease by using a patient's own immune system. The promising results …
Personalized dendritic cell vaccines—recent breakthroughs and encouraging clinical results
B Mastelic-Gavillet, K Balint, C Boudousquie… - Frontiers in …, 2019 - frontiersin.org
With the advent of combined immunotherapies, personalized dendritic cell (DC)-based
vaccination could integrate the current standard of care for the treatment of a large variety of …
vaccination could integrate the current standard of care for the treatment of a large variety of …
Taking dendritic cells into medicine
RM Steinman, J Banchereau - Nature, 2007 - nature.com
Dendritic cells (DCs) orchestrate a repertoire of immune responses that bring about
resistance to infection and silencing or tolerance to self. In the settings of infection and …
resistance to infection and silencing or tolerance to self. In the settings of infection and …