Microfluidic formulation of topological hydrogels for microtissue engineering

KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

[HTML][HTML] Advanced hydrogels for the repair of cartilage defects and regeneration

W Wei, Y Ma, X Yao, W Zhou, X Wang, C Li, J Lin… - Bioactive materials, 2021 - Elsevier
Cartilage defects are one of the most common symptoms of osteoarthritis (OA), a
degenerative disease that affects millions of people world-wide and places a significant …

Spheroid culture system methods and applications for mesenchymal stem cells

NE Ryu, SH Lee, H Park - Cells, 2019 - mdpi.com
Owing to the importance of stem cell culture systems in clinical applications, researchers
have extensively studied them to optimize the culture conditions and increase efficiency of …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Cell culture in microfluidic droplets

S Sart, G Ronteix, S Jain, G Amselem… - Chemical …, 2022 - ACS Publications
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

Granular hydrogels in biofabrication: recent advances and future perspectives

AC Daly - Advanced Healthcare Materials, 2024 - Wiley Online Library
Granular hydrogels, which are formed by densely packing microgels, are promising
materials for bioprinting due to their extrudability, porosity, and modularity. However, the …

Stem cell‐recruiting injectable microgels for repairing osteoarthritis

Y Lei, Y Wang, J Shen, Z Cai, Y Zeng… - Advanced functional …, 2021 - Wiley Online Library
The differentiation potentials and viability of stem cells are often impaired during cell
isolation and delivery. Inspired by the phenomenon where islands can recruit seabirds for …

Injectable MSC spheroid and microgel granular composites for engineering tissue

ND Caprio, MD Davidson, AC Daly… - Advanced …, 2024 - Wiley Online Library
Many cell types require direct cell–cell interactions for differentiation and function; yet, this
can be challenging to incorporate into 3‐dimensional (3D) structures for the engineering of …

Free and hydrogel encapsulated exosome-based therapies in regenerative medicine

A Akbari, N Jabbari, R Sharifi, M Ahmadi, A Vahhabi… - Life sciences, 2020 - Elsevier
Over the last few decades, mesenchymal stem cells-derived exosomes (MSCs-Ex) have
attracted a lot of attention as a therapeutic tool in regenerative medicine. Exosomes are …

[HTML][HTML] Emerging biofabrication techniques: A review on natural polymers for biomedical applications

M Puertas-Bartolomé, A Mora-Boza… - Polymers, 2021 - mdpi.com
Natural polymers have been widely used for biomedical applications in recent decades.
They offer the advantages of resembling the extracellular matrix of native tissues and …