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Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …
epigenetic level can be considered as important drivers. Epigenetic factors include a large …
Colorectal carcinoma: a general overview and future perspectives in colorectal cancer
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
J Ren, L Ding, D Zhang, G Shi, Q Xu, S Shen… - …, 2018 - pmc.ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …
Therapeutic targeting of long non-coding RNAs in cancer
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma
Z Sun, S Xue, M Zhang, H Xu, X Hu, S Chen, Y Liu… - Oncogene, 2020 - nature.com
RNA methylation is an important epigenetic modification. Recent studies on RNA
methylation mainly focus on the m6A modification of mRNA, but very little is known about the …
methylation mainly focus on the m6A modification of mRNA, but very little is known about the …
The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy
J Wang, S **e, J Yang, H **ong, Y Jia, Y Zhou… - Journal of hematology & …, 2019 - Springer
Background Tamoxifen resistance remains a clinical challenge for hormone receptor-
positive breast cancer. Recently, dysregulations in autophagy have been suggested as a …
positive breast cancer. Recently, dysregulations in autophagy have been suggested as a …
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
Recently, the long non-coding RNA (lncRNA) H19 has been identified as an oncogenic
gene in multiple cancer types and elevated expression of H19 was tightly linked to …
gene in multiple cancer types and elevated expression of H19 was tightly linked to …
Colorectal cancer carcinogenesis: a review of mechanisms
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …
common in men globally. CRC arises from one or a combination of chromosomal instability …
MicroRNA as an important target for anticancer drug development
Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …
several different classes of anticancer drugs that are available in clinic, some tough issues …
Interaction and cross-talk between non-coding RNAs
S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …