Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy

M Hashemi, MS Moosavi, HM Abed, M Dehghani… - Pharmacological …, 2022 - Elsevier
Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19

J Ren, L Ding, D Zhang, G Shi, Q Xu, S Shen… - …, 2018 - pmc.ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Therapeutic targeting of long non-coding RNAs in cancer

G Arun, SD Diermeier, DL Spector - Trends in molecular medicine, 2018 - cell.com
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …

Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma

Z Sun, S Xue, M Zhang, H Xu, X Hu, S Chen, Y Liu… - Oncogene, 2020 - nature.com
RNA methylation is an important epigenetic modification. Recent studies on RNA
methylation mainly focus on the m6A modification of mRNA, but very little is known about the …

The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy

J Wang, S **e, J Yang, H **ong, Y Jia, Y Zhou… - Journal of hematology & …, 2019 - Springer
Background Tamoxifen resistance remains a clinical challenge for hormone receptor-
positive breast cancer. Recently, dysregulations in autophagy have been suggested as a …

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

WC Liang, WM Fu, CW Wong, Y Wang, WM Wang… - …, 2015 - pmc.ncbi.nlm.nih.gov
Recently, the long non-coding RNA (lncRNA) H19 has been identified as an oncogenic
gene in multiple cancer types and elevated expression of H19 was tightly linked to …

Colorectal cancer carcinogenesis: a review of mechanisms

K Tariq, K Ghias - Cancer biology & medicine, 2016 - cancerbiomed.org
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …

MicroRNA as an important target for anticancer drug development

Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …