Physics of liquid crystals in cell biology

A Doostmohammadi, B Ladoux - Trends in cell biology, 2022 - cell.com
The past decade has witnessed a rapid growth in understanding of the pivotal roles of
mechanical stresses and physical forces in cell biology. As a result, an integrated view of …

Topology-guided polar ordering of collective cell migration

E Lång, A Lång, P Blicher, T Rognes… - Science …, 2024 - science.org
The ability of epithelial monolayers to self-organize into a dynamic polarized state, where
cells migrate in a uniform direction, is essential for tissue regeneration, development, and …

Robust Edge Flows in Swarming Bacterial Colonies

H Li, H Chaté, M Sano, X Shi, HP Zhang - Physical Review X, 2024 - APS
Understanding if and how the chirality of biomolecules is transferred across scales into
larger components and active processes remains elusive. For instance, flagellated bacteria …

Tissue Active Matter: Integrating Mechanics and Signaling into Dynamical Models

DB Brückner, E Hannezo - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The importance of physical forces in the morphogenesis, homeostatic function, and
pathological dysfunction of multicellular tissues is being increasingly characterized, both …

Stress-shape misalignment in confluent cell layers

MR Nejad, LJ Ruske, M McCord, J Zhang… - Nature …, 2024 - nature.com
In tissue formation and repair, the epithelium undergoes complex patterns of motion driven
by the active forces produced by each cell. Although the principles governing how the forces …

A shape-driven reentrant jamming transition in confluent monolayers of synthetic cell-mimics

P Arora, S Sadhukhan, SK Nandi, D Bi… - Nature …, 2024 - nature.com
Many critical biological processes, like wound healing, require densely packed cell
monolayers/tissues to transition from a jammed solid-like to a fluid-like state. Although …

Chirotactic response of microswimmers in fluids with odd viscosity

Y Hosaka, M Chatzittofi, R Golestanian, A Vilfan - Physical Review Research, 2024 - APS
Odd viscosity is a property of chiral active fluids with broken time-reversal and parity
symmetries. We show that the flow of such a fluid around a rotating axisymmetric body is …

Chiral active membranes: Odd mechanics, spontaneous flows, and shape instabilities

SC Al-Izzi, GP Alexander - Physical Review Research, 2023 - APS
Living systems are chiral on multiple scales, from constituent biopolymers to large scale
morphology, and their active mechanics is both driven by chiral components and serves to …

Geometry-induced dynamics of confined chiral active matter

A Negi, K Beppu, YT Maeda - Physical Review Research, 2023 - APS
Controlling the motion of active matter is a central issue that has recently garnered
significant attention in fields ranging from nonequilibrium physics to chemical engineering …

Emergence of macroscopic directional motion of deformable active cells in confined structures

B Ai, J Ma, C Zeng, Y He - Physical Review E, 2023 - APS
There is now growing evidence of collective turbulentlike motion of cells in dense tissues.
However, how to control and harness this collective motion is an open question. We …