Recent advances in synthetic biology for engineering isoprenoid production in yeast
Highlights•Isoprenoids are industrially important natural products.•Yeast are key industrial
production vehicles.•New synthetic biology approaches in recent years are reviewed.•Future …
production vehicles.•New synthetic biology approaches in recent years are reviewed.•Future …
Design automation in synthetic biology
Design automation refers to a category of software tools for designing systems that work
together in a workflow for designing, building, testing, and analyzing systems with a target …
together in a workflow for designing, building, testing, and analyzing systems with a target …
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora… - US Patent …, 2018 - Google Patents
2017-02-28 Assigned to Zymergen, Inc. reassignment Zymergen, Inc. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SHELLMAN, ERIN …
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SHELLMAN, ERIN …
High-throughput functional variant screens via in vivo production of single-stranded DNA
Creating and characterizing individual genetic variants remains limited in scale, compared
to the tremendous variation both existing in nature and envisioned by genome engineers …
to the tremendous variation both existing in nature and envisioned by genome engineers …
Sharing structure and function in biological design with SBOL 2.0
The Synthetic Biology Open Language (SBOL) is a standard that enables collaborative
engineering of biological systems across different institutions and tools. SBOL is developed …
engineering of biological systems across different institutions and tools. SBOL is developed …
Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration
LBA Woodruff, TE Gorochowski… - Nucleic Acids …, 2017 - academic.oup.com
Genetic designs can consist of dozens of genes and hundreds of genetic parts. After
evaluating a design, it is desirable to implement changes without the cost and burden of …
evaluating a design, it is desirable to implement changes without the cost and burden of …
Needs and opportunities in bio-design automation: four areas for focus
Bio-design automation (BDA) is an emerging field focused on computer-aided design,
engineering principles, and automated manufacturing of biological systems. Here we …
engineering principles, and automated manufacturing of biological systems. Here we …
An automated scientist to design and optimize microbial strains for the industrial production of small molecules
Engineering microbes to synthesize molecules of societal value has historically been a time
consuming and artisanal process, with the synthesis of each new non-native molecule …
consuming and artisanal process, with the synthesis of each new non-native molecule …
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora… - US Patent …, 2019 - Google Patents
2018-04-05 Assigned to ZYMERGEN INC. reassignment ZYMERGEN INC. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SERBER, ZACH …
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SERBER, ZACH …
Microbial strain improvement by a HTP genomic engineering platform
Z Serber, EJ Dean, S Manchester, K Gora… - US Patent …, 2018 - Google Patents
2018-04-05 Assigned to ZYMERGEN INC. reassignment ZYMERGEN INC. ASSIGNMENT
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SERBER, ZACH …
OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SERBER, ZACH …