Despite their remarkable biosynthetic potential, Bacillus subtilis have been widely
overlooked. However, their capability to withstand harsh conditions (extreme temperature …

Bacillus subtilis is widely underappreciated for its inherent biosynthetic potential. This report
comprehensively summarizes the known bioactive secondary metabolites from B. subtilis …

Single particle electron cryomicroscopy (cryo-EM) has recently made significant progress in
high-resolution structure determination of macromolecular complexes due to improvements …

Protein synthesis by the ribosome is highly dependent on the ionic conditions in the cellular
environment, but the roles of ribosome solvation have remained poorly understood …

Genetic information is translated into proteins by the ribosome. Structural studies of the
ribosome and of its complexes with factors and inhibitors have provided invaluable …

Protein synthesis occurs on macromolecular machines, called ribosomes. Bacterial
ribosomes and the translational machinery represent one of the major targets for antibiotics …

With bacterial resistance becoming a serious threat to global public health, antimicrobial
peptides (AMPs) have become a promising area of focus in antibiotic research. AMPs are …

Covering: up to November 2017 Organismic interaction is one of the fundamental principles
for survival in any ecosystem. Today, numerous examples show the interaction between …

Microbiome spectra serve as critical clues to elucidate the evolutionary biology pathways,
potential pathologies, and even behavioral patterns of the host organisms. Furthermore …

Lasso peptides are ribosomally synthesized and post-translationally modified peptide
(RiPP) natural products that display a unique lariat-like, threaded conformation. Owing to a …