In India, increasing lifespan and decreasing fertility rates have resulted in a growing number
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …

Background In recent decades, increased attention has been paid to the impact of
socioeconomic status (SES) on cognition function and dementia, however, an ongoing …

Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide …

We developed an endophenotype disease module-based methodology for Alzheimer's
disease (AD) drug repurposing and identified sildenafil as a potential disease risk modifier …

Background Modifiable risk factor estimates are sparse for early-onset dementia incidence.
This study aimed to estimate and compare the risk factor profiles of early-onset dementia …

Social determinants of health are the conditions in which people are born, work, live, and
age and the wider set of forces and systems that shape the conditions of daily life. They …

Aging involves decline in a range of functional abilities and phenotypes, many of which are
also associated with socioeconomic status (SES). Here we assessed whether lower SES is …

In a world with an ageing population, dementia has become an urgent threat to global health
and wellbeing. Psychosocial and lifestyle factors, such as higher socioeconomic positions …

Abstract Purpose of Review The aim of this review is to summarize current conceptual
models of cognitive reserve (CR) and related concepts and to discuss evidence for these …

Background: Differences in dementia risk across the gradient of socioeconomic status (SES)
exist, but their determinants are not well understood. Objective: This study investigates …