It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

Somlyo, Andrew P., and Avril V. Somlyo. Ca2+ Sensitivity of Smooth Muscle and Nonmuscle
Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase. Physiol Rev 83 …

Anti-inflammatory drugs are used to relieve pain, fever, and inflammation while protecting
the cardiovascular system. However, the side effects of currently available medications have …

The cerebral vascular system services the constant demand for energy during neuronal
activity in the brain. Attempts to delineate the logic of neurovascular coupling have been …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents,
both autonomic and somatic, and supraspinal influences from visual, olfactory, and …

Caffeine is the most widely consumed stimulating substance in the world. It is found in
coffee, tea, soft drinks, chocolate, and many medications. Caffeine is a xanthine with various …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but
also by visual, olfactory, and imaginary stimuli. The reflex involves both autonomic and …

KCl has long been used as a convenient stimulus to bypass G protein-coupled receptors
(GPCR) and activate smooth muscle by a highly reproducible and relatively “simple” …

Last decade has seen a growing trend toward smartphone-based biochemical sensing
systems. Meanwhile, flexible electrochemical sensing devices like wristbands, patches, and …

Vascular smooth muscle tone is controlled by a balance between the cellular signaling
pathways that mediate the generation of force (vasoconstriction) and release of force …