Abstract Ergothioneine, Ovothiol, and Selenoneine are sulfur/selenium-containing histidine-
derived natural products widely distributed across different organisms. They exhibit …

Living organisms have evolved various strategies to incorporate sulfur and selenium into
bioactive natural products. These chalcogen-containing compounds serve important and …

Biosynthesis is an environmentally benign and renewable approach that can be used to
produce a broad range of natural and, in some cases, new-to-nature products. However …

Ovothiol A and ergothioneine are thiol-histidine derivatives with sulfur substitutions at the δ-
carbon or ε-carbon of the l-histidine imidazole ring, respectively. Both ovothiol A and …

Organoselenium compounds are rare in nature but play important physiological roles by
exploiting the distinct features of selenium. However, the ability to explore these compounds …

The P450 monooxygenase TleB (CYP107E48) catalyzes intramolecular C–S bond
formation in a thiol-containing substrate, yielding two sulfur-containing indolactam …

The concept of genetic code expansion (GCE) has revolutionized the field of chemical and
synthetic biology, enabling the site-specific incorporation of noncanonical amino acids …

Carbenes are highly reactive compounds with unique value to synthetic chemistry. However,
a small number of natural enzymes have been shown to utilize carbene chemistry, and …

Mononuclear non-heme iron enzymes are a large class of enzymes catalyzing a wide-range
of reactions. In this work, we report that a non-heme iron enzyme in Methyloversatilis …

Molecules | Free Full-Text | Ergothioneine, Ovothiol A, and Selenoneine—Histidine-Derived,
Biologically Significant, Trace Global Alkaloids Next Article in Journal Analysis of …