Global map** of cancers: The Cancer Genome Atlas and beyond

C Ganini, I Amelio, R Bertolo, P Bove… - Molecular …, 2021 - Wiley Online Library
Cancer genomes have been explored from the early 2000s through massive exome
sequencing efforts, leading to the publication of The Cancer Genome Atlas in 2013 …

The p53 family member p73 in the regulation of cell stress response

JM Rozenberg, S Zvereva, A Dalina, I Blatov, I Zubarev… - Biology direct, 2021 - Springer
During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …

Glutathione efflux and cell death

R Franco, JA Cidlowski - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Glutathione (GSH) depletion is a central signaling event that regulates the
activation of cell death pathways. GSH depletion is often taken as a marker of oxidative …

Allium vegetables for possible future of cancer treatment

Y Asemani, N Zamani, M Bayat… - Phytotherapy …, 2019 - Wiley Online Library
Natural resources such as plants are an upright curing option in treating cancers and
reducing the side effects of current therapeutic modalities. Allium genus vegetables are of …

Low level of plasminogen increases risk for mortality in COVID-19 patients

D Della-Morte, F Pacifici, C Ricordi, R Massoud… - Cell death & …, 2021 - nature.com
The pathophysiology of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), and especially of its complications is still …

Total neoadjuvant therapy for the treatment of locally advanced rectal cancer: a systematic minireview

AM Guida, B Sensi, V Formica, RM D'Angelillo… - Biology Direct, 2022 - Springer
Colorectal carcinoma is the second leading cause of cancer-related deaths, and indeed,
rectal cancer accounting for approximately one third of newly diagnosed patients. Gold …

Motor cortex glutathione deficit in ALS measured in vivo with the J-editing technique

N Weiduschat, X Mao, J Hupf, N Armstrong, G Kang… - Neuroscience …, 2014 - Elsevier
This study compared in vivo levels of the antioxidant glutathione (GSH) in the motor cortex of
11 ALS patients with those in 11 age-matched healthy volunteers (HV). Using the standard J …

Definition and reporting of lymphadenectomy and complete mesocolic excision for radical right colectomy: a systematic review

GS Sica, D Vinci, L Siragusa, B Sensi, AM Guida… - Surgical …, 2023 - Springer
Background Several procedures have been proposed to reduce the rates of recurrence in
patients with right-sided colon cancer. Different procedures for a radical right colectomy …

Distinct interactors define the p63 transcriptional signature in epithelial development or cancer

R Pecorari, F Bernassola, G Melino… - Biochemical …, 2022 - portlandpress.com
The TP63 is an indispensable transcription factor for development and homeostasis of
epithelia and its derived glandular tissue. It is also involved in female germline cell quality …

The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells

CH Kaschula, R Tuveri, E Ngarande, K Dzobo… - BMC cancer, 2019 - Springer
Background Garlic has been used for centuries for its flavour and health promoting
properties that include protection against cancer. The vinyl disulfide-sulfoxide ajoene is one …