Epigenetic regulation of immune cells in systemic lupus erythematosus: insight from chromatin accessibility

ZX Gao, T He, P Zhang, X Hu, M Ge, YQ Xu… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Systemic Lupus Erythematosus (SLE) is a multi-dimensional
autoimmune disease involving numerous tissues throughout the body. The chromatin …

Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort

MJ Divo, BR Celli, B Poblador-Plou… - PloS one, 2018 - journals.plos.org
Background Aging is an important risk factor for most chronic diseases. Patients with COPD
develop more comorbidities than non-COPD subjects. We hypothesized that the …

Inhibitory effect of **wujiangu prescription on peripheral blood osteoclasts in patients with rheumatoid arthritis and the relevant molecular mechanism

Y Huang, X Gao, Y An, P Zeng, C Chen… - Mediators of …, 2023 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease characterized with
high recurrence, high disability, poor prognosis, and long treatment cycles. Versus western …

Integrated analysis of ATAC-seq and RNA-seq reveals the chromatin accessibility and transcriptional landscape of immunoglobulin a nephropathy

ZX Gao, Y Fang, SZ Xu, YS He, M Ge, P Zhang… - Clinical …, 2025 - Elsevier
Backgrounds The association between chromatin accessibility in CD4+ T cells and
Immunoglobulin A nephropathy (IgAN) remains unclear. Methods We performed the assay …

Corydalis decumbens and tetrahydropalmatrubin inhibit macrophages inflammation to relieve rheumatoid arthritis by targeting Fosl2

P Gao, S Yuan, Y Wang, Y Wang, X Li, T Liu… - Journal of …, 2025 - Elsevier
Abstract Ethnopharmacological relevance Corydalis decumbens (Thunb.)(CD) is a
traditional Chinese medicine and as a single herb or formula has been used to treat RA for …

Analyzation of the peripheral blood mononuclear cells atlas and cell communication of rheumatoid arthritis patients based on single‐cell RNA‐Seq

X Song, Y Zhang, L Zhao, J Fan, T Peng… - Journal of …, 2023 - Wiley Online Library
Background. Rheumatoid arthritis (RA) is a common chronic inflammatory autoimmune
disease with a multifactorial etiology. Peripheral blood is the main channel of the immune …

[HTML][HTML] Interleukin-6 and Interleukin-8 Gene Expressions Differ Between Male and Female Patients at Time of Hip Arthroscopy for Femoroacetabular Im**ement …

AM Spiker, JA Choe, EHG Turner, R Vanderby… - … , Sports Medicine, and …, 2024 - Elsevier
Purpose To identify key molecular components within the femoroacetabular im**ement
hip and compare the findings between male and female patients across varying age groups …

Gene regulatory network study of rheumatoid arthritis in single-cell chromatin landscapes of peripheral blood mononuclear cells

C Zhang, X Hong, H Yu, H Xu, X Qiu, W Cai… - Modern …, 2023 - academic.oup.com
Objectives Assays for transposase-accessible chromatin with single-cell sequencing
(scATAC-seq) contribute to the progress in epigenetic studies. The purpose of our project …

Progress and application on severe combined immunodeficiency mouse model for rheumatoid arthritis: a literature review

Z Li, R Yao, Y Ying, J Qian, Y Shen, L Gao… - Revista da Associação …, 2021 - SciELO Brasil
Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease1 that can affect
many tissues and organs, such as the heart and kidneys. Its pathogenesis is not completely …

A Multiomic Study of Epigenetic Dysregulation in Chronic Myelomonocytic Leukaemia

HM Bossenbroek - 2023 - search.proquest.com
Chronic myelomonocytic leukaemia (CMML) is a clonal haematological neoplasm
characterised by persistent monocytosis and dysplasia in at least one myeloid lineage. It can …