Autophagy regulation by inorganic, organic, and organic/inorganic hybrid nanoparticles: organelle damage, regulation factors, and potential pathways
D Qiao, T Zhang, M Tang - Journal of Biochemical and …, 2023 - Wiley Online Library
The rapid development of nanotechnology requires a more thorough understanding of the
potential health effects caused by nanoparticles (NPs). As a programmed cell death …
potential health effects caused by nanoparticles (NPs). As a programmed cell death …
Impacts and potential mechanisms of fine particulate matter (PM2.5) on male testosterone biosynthesis disruption
S Zheng, N Zhao, X Lin, L Qiu - Reviews on Environmental Health, 2024 - degruyter.com
Exposure to PM2. 5 is the most significant air pollutant for health risk. The testosterone level
in male is vulnerable to environmental toxicants. In the past, researchers focused more …
in male is vulnerable to environmental toxicants. In the past, researchers focused more …
Silica nanoparticles promote apoptosis in ovarian granulosa cells via autophagy dysfunction
Z Zheng, W Zuo, R Ye, JW Grunberger… - International Journal of …, 2023 - mdpi.com
Although silica nanoparticles (SNPs) are generally thought to be biocompatible and safe,
the adverse effects of SNPs were also reported in previous studies. SNPs cause follicular …
the adverse effects of SNPs were also reported in previous studies. SNPs cause follicular …
METTL3-m6A-SIRT1 axis affects autophagic flux contributing to PM2. 5-induced inhibition of testosterone production in Leydig cells
L Jiang, X Lin, J Jiang, C Qiu, S Zheng, N Zhao… - Science of The Total …, 2024 - Elsevier
Epidemiological studies have found that long-term inhalation of PM2. 5 is closely related to
spermatogenesis disorders and infertility, but the underlying molecular mechanism is still …
spermatogenesis disorders and infertility, but the underlying molecular mechanism is still …
Silica nanoparticles induce ovarian granulosa cell apoptosis via activation of the PERK-ATF4-CHOP-ERO1α pathway-mediated IP3R1-dependent calcium …
F Chen, J Sun, Y Wang, JW Grunberger… - Cell Biology and …, 2023 - Springer
Ambient particulate matters (PMs) have adverse effects in human and animal female
reproductive health. Silica nanoparticles (SNPs), as a major component of PMs, can induce …
reproductive health. Silica nanoparticles (SNPs), as a major component of PMs, can induce …
Functional role of autophagy in testicular and ovarian steroidogenesis
Autophagy is an evolutionarily conserved cellular recycling process that maintains cellular
homeostasis. Despite extensive research in endocrine contexts, the role of autophagy in …
homeostasis. Despite extensive research in endocrine contexts, the role of autophagy in …
[HTML][HTML] Taurine Protects against Silica Nanoparticle-Induced Apoptosis and Inflammatory Response via Inhibition of Oxidative Stress in Porcine Ovarian Granulosa …
F Chen, J Sun, R Ye, TL Virk, Q Liu, Y Yuan, X Xu - Animals, 2024 - mdpi.com
Simple Summary Taurine (Tau) is a well-known antioxidant. However, the protective effects
of Tau against silica nanoparticle (SNP)-induced reproductive toxicity still remain …
of Tau against silica nanoparticle (SNP)-induced reproductive toxicity still remain …
Melatonin counteracts cadmium‐induced rat testicular toxicity via the mechanistic target rapamycin (mTOR) pathway
MB Rhouma, M Venditti, A Haddadi… - … Zoology Part A …, 2024 - Wiley Online Library
The protective action of melatonin (MLT) against the harmful effects of cadmium (Cd) on
testicular activity in rats has been documented previously; however, the involved molecular …
testicular activity in rats has been documented previously; however, the involved molecular …
BECLIN-1-mediated autophagy suppresses silica nanoparticle-induced testicular toxicity via the inhibition of caspase 8-mediated cell apoptosis in leydig cells
Accumulation of silica nanoparticles (SNPs) in the testes leads to male reproductive toxicity.
However, little is known about the effect and mechanistic insights of SNP-induced …
However, little is known about the effect and mechanistic insights of SNP-induced …
Hydroxysafflor Yellow A (HSYA) Protects Endplate Chondrocytes Against IL‐1β‐Induced Injury Through Promoting Autophagy
Z Zhang, Y Huo, Z Zhou, P Zhang… - … and Alternative Medicine, 2022 - Wiley Online Library
Background. Intervertebral disc degeneration (IDD) refers to intractable pain in patients'
waist and legs, which is caused by internal structural disorder and degeneration of …
waist and legs, which is caused by internal structural disorder and degeneration of …